Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | NW969_RS05585 | Genome accession | NZ_CP102958 |
| Coordinates | 1181310..1182182 (+) | Length | 290 a.a. |
| NCBI ID | WP_000931872.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain 15-G-54 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1144429..1204972 | 1181310..1182182 | within | 0 |
Gene organization within MGE regions
Location: 1144429..1204972
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NW969_RS05420 (NW969_05420) | - | 1144736..1144939 (-) | 204 | WP_001198020.1 | TM2 domain-containing protein | - |
| NW969_RS05425 (NW969_05425) | - | 1145238..1145726 (+) | 489 | WP_000985290.1 | peptide deformylase | - |
| NW969_RS05430 (NW969_05430) | fmt | 1145719..1146654 (+) | 936 | WP_258414133.1 | methionyl-tRNA formyltransferase | - |
| NW969_RS05435 (NW969_05435) | rsmB | 1146651..1147958 (+) | 1308 | WP_258414134.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| NW969_RS05440 (NW969_05440) | rlmN | 1147961..1149055 (+) | 1095 | WP_000626897.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| NW969_RS05445 (NW969_05445) | - | 1149062..1149805 (+) | 744 | WP_000888494.1 | protein-serine/threonine phosphatase Stp1 | - |
| NW969_RS05450 (NW969_05450) | pknB | 1149802..1151796 (+) | 1995 | WP_258414135.1 | serine/threonine protein kinase Stk1 | - |
| NW969_RS05455 (NW969_05455) | rsgA | 1152024..1152899 (+) | 876 | WP_000847936.1 | ribosome small subunit-dependent GTPase A | - |
| NW969_RS05460 (NW969_05460) | rpe | 1152900..1153544 (+) | 645 | WP_000164332.1 | ribulose-phosphate 3-epimerase | - |
| NW969_RS05465 (NW969_05465) | - | 1153551..1154192 (+) | 642 | WP_000547905.1 | thiamine diphosphokinase | - |
| NW969_RS05470 (NW969_05470) | rpmB | 1154573..1154761 (-) | 189 | WP_000517908.1 | 50S ribosomal protein L28 | - |
| NW969_RS05475 (NW969_05475) | - | 1155204..1155578 (+) | 375 | WP_000171418.1 | Asp23/Gls24 family envelope stress response protein | - |
| NW969_RS05480 (NW969_05480) | fakA | 1155593..1157239 (+) | 1647 | WP_000623903.1 | fatty acid kinase catalytic subunit FakA | - |
| NW969_RS05485 (NW969_05485) | recG | 1157429..1159489 (+) | 2061 | WP_001151497.1 | ATP-dependent DNA helicase RecG | - |
| NW969_RS05490 (NW969_05490) | fapR | 1159838..1160410 (+) | 573 | WP_001548538.1 | transcription factor FapR | - |
| NW969_RS05495 (NW969_05495) | plsX | 1160415..1161401 (+) | 987 | WP_154284349.1 | phosphate acyltransferase PlsX | - |
| NW969_RS05500 (NW969_05500) | fabD | 1161394..1162320 (+) | 927 | WP_209205895.1 | ACP S-malonyltransferase | - |
| NW969_RS05505 (NW969_05505) | fabG | 1162313..1163047 (+) | 735 | WP_000167269.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| NW969_RS05510 (NW969_05510) | - | 1163550..1163783 (+) | 234 | WP_000426914.1 | acyl carrier protein | - |
| NW969_RS05515 (NW969_05515) | rnc | 1163899..1164630 (+) | 732 | WP_000043237.1 | ribonuclease III | - |
| NW969_RS05520 (NW969_05520) | smc | 1164777..1168343 (+) | 3567 | WP_258414136.1 | chromosome segregation protein SMC | - |
| NW969_RS05525 (NW969_05525) | ftsY | 1168343..1169593 (+) | 1251 | WP_000007687.1 | signal recognition particle-docking protein FtsY | - |
| NW969_RS05530 (NW969_05530) | - | 1169580..1169912 (+) | 333 | WP_000531320.1 | putative DNA-binding protein | - |
| NW969_RS05535 (NW969_05535) | ffh | 1169938..1171305 (+) | 1368 | WP_258414137.1 | signal recognition particle protein | - |
| NW969_RS05540 (NW969_05540) | rpsP | 1171740..1172015 (+) | 276 | WP_000268754.1 | 30S ribosomal protein S16 | - |
| NW969_RS05545 (NW969_05545) | rimM | 1172203..1172706 (+) | 504 | WP_001261987.1 | ribosome maturation factor RimM | - |
| NW969_RS05550 (NW969_05550) | trmD | 1172706..1173443 (+) | 738 | WP_000687328.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| NW969_RS05555 (NW969_05555) | rplS | 1173546..1173896 (+) | 351 | WP_000181404.1 | 50S ribosomal protein L19 | - |
| NW969_RS05560 (NW969_05560) | yfhO | 1174139..1176745 (-) | 2607 | WP_258414138.1 | lipoteichoic acid-specific glycosyltransferase YfhO | - |
| NW969_RS05565 (NW969_05565) | ylqF | 1177146..1178030 (+) | 885 | WP_000236722.1 | ribosome biogenesis GTPase YlqF | - |
| NW969_RS05570 (NW969_05570) | - | 1178014..1178781 (+) | 768 | WP_000176393.1 | ribonuclease HII | - |
| NW969_RS05575 (NW969_05575) | sucC | 1178890..1180056 (+) | 1167 | WP_001020801.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| NW969_RS05580 (NW969_05580) | sucD | 1180078..1180986 (+) | 909 | WP_000110251.1 | succinate--CoA ligase subunit alpha | - |
| NW969_RS05585 (NW969_05585) | dprA | 1181310..1182182 (+) | 873 | WP_000931872.1 | DNA-processing protein DprA | Machinery gene |
| NW969_RS05590 (NW969_05590) | topA | 1182356..1184431 (+) | 2076 | WP_001557331.1 | type I DNA topoisomerase | - |
| NW969_RS05595 (NW969_05595) | trmFO | 1184587..1185894 (+) | 1308 | WP_000195259.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| NW969_RS05600 (NW969_05600) | xerC | 1186311..1187207 (+) | 897 | WP_001015598.1 | tyrosine recombinase XerC | - |
| NW969_RS05605 (NW969_05605) | hslV | 1187204..1187749 (+) | 546 | WP_000072681.1 | ATP-dependent protease subunit HslV | - |
| NW969_RS05610 (NW969_05610) | hslU | 1187815..1189218 (+) | 1404 | WP_000379054.1 | ATP-dependent protease ATPase subunit HslU | - |
| NW969_RS05615 (NW969_05615) | codY | 1189243..1190016 (+) | 774 | WP_000055337.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| NW969_RS05620 (NW969_05620) | - | 1190067..1190159 (+) | 93 | WP_031788481.1 | hypothetical protein | - |
| NW969_RS05625 (NW969_05625) | rpsB | 1190358..1191125 (+) | 768 | WP_000268484.1 | 30S ribosomal protein S2 | - |
| NW969_RS05630 (NW969_05630) | - | 1191159..1191272 (+) | 114 | WP_001789890.1 | hypothetical protein | - |
| NW969_RS05635 (NW969_05635) | tsf | 1191307..1192188 (+) | 882 | WP_072497235.1 | translation elongation factor Ts | - |
| NW969_RS05640 (NW969_05640) | pyrH | 1192325..1193047 (+) | 723 | WP_000057330.1 | UMP kinase | - |
| NW969_RS05645 (NW969_05645) | frr | 1193066..1193620 (+) | 555 | WP_001280006.1 | ribosome recycling factor | - |
| NW969_RS05650 (NW969_05650) | - | 1193993..1194763 (+) | 771 | WP_000473705.1 | isoprenyl transferase | - |
| NW969_RS05655 (NW969_05655) | - | 1194770..1195552 (+) | 783 | WP_000868413.1 | phosphatidate cytidylyltransferase | - |
| NW969_RS05660 (NW969_05660) | rseP | 1195764..1197050 (+) | 1287 | WP_000121122.1 | RIP metalloprotease RseP | - |
| NW969_RS05665 (NW969_05665) | - | 1197070..1198773 (+) | 1704 | WP_000814094.1 | proline--tRNA ligase | - |
| NW969_RS05670 (NW969_05670) | - | 1199037..1203347 (+) | 4311 | WP_258414155.1 | PolC-type DNA polymerase III | - |
| NW969_RS05675 (NW969_05675) | rimP | 1203637..1204104 (+) | 468 | WP_000036631.1 | ribosome maturation factor RimP | - |
Sequence
Protein
Download Length: 290 a.a. Molecular weight: 33212.51 Da Isoelectric Point: 8.3112
>NTDB_id=720452 NW969_RS05585 WP_000931872.1 1181310..1182182(+) (dprA) [Staphylococcus aureus strain 15-G-54]
MLNHILLKLIWSRFTTAQIHLLLKTFPSCCEVDEYERMHILENFCKLLADKKIDAKVNRYKEISVDEIETTIQKTQLNYI
TCFDHNYPYLLKETYNYPIILFYKGNINLLSYPHTLAVVGSRLSGDYTLKALNHLFVSFQQMSFCVVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
MLNHILLKLIWSRFTTAQIHLLLKTFPSCCEVDEYERMHILENFCKLLADKKIDAKVNRYKEISVDEIETTIQKTQLNYI
TCFDHNYPYLLKETYNYPIILFYKGNINLLSYPHTLAVVGSRLSGDYTLKALNHLFVSFQQMSFCVVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
Nucleotide
Download Length: 873 bp
>NTDB_id=720452 NW969_RS05585 WP_000931872.1 1181310..1182182(+) (dprA) [Staphylococcus aureus strain 15-G-54]
ATGTTAAATCACATTTTACTTAAATTAATTTGGAGTCGTTTTACTACTGCACAAATACATCTACTTTTAAAAACTTTTCC
AAGTTGTTGTGAAGTAGATGAATATGAACGAATGCATATTCTAGAAAATTTTTGTAAGCTTTTAGCGGATAAAAAAATAG
ATGCTAAAGTTAACCGTTACAAGGAAATTTCTGTTGATGAAATTGAAACAACAATTCAGAAAACCCAATTAAATTATATA
ACTTGTTTTGATCATAATTATCCCTATTTATTAAAAGAAACTTACAATTATCCTATCATTTTGTTCTATAAAGGGAATAT
TAACCTCCTTAGTTATCCGCACACTTTAGCTGTCGTTGGGTCACGATTATCAGGCGACTATACTTTAAAGGCATTGAATC
ATCTCTTCGTTTCATTTCAACAAATGAGTTTCTGTGTTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
ATGTTAAATCACATTTTACTTAAATTAATTTGGAGTCGTTTTACTACTGCACAAATACATCTACTTTTAAAAACTTTTCC
AAGTTGTTGTGAAGTAGATGAATATGAACGAATGCATATTCTAGAAAATTTTTGTAAGCTTTTAGCGGATAAAAAAATAG
ATGCTAAAGTTAACCGTTACAAGGAAATTTCTGTTGATGAAATTGAAACAACAATTCAGAAAACCCAATTAAATTATATA
ACTTGTTTTGATCATAATTATCCCTATTTATTAAAAGAAACTTACAATTATCCTATCATTTTGTTCTATAAAGGGAATAT
TAACCTCCTTAGTTATCCGCACACTTTAGCTGTCGTTGGGTCACGATTATCAGGCGACTATACTTTAAAGGCATTGAATC
ATCTCTTCGTTTCATTTCAACAAATGAGTTTCTGTGTTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
65.677 |
100 |
0.686 |
| dprA | Staphylococcus aureus N315 |
66.897 |
100 |
0.669 |
| dprA | Lactococcus lactis subsp. cremoris KW2 |
38.214 |
96.552 |
0.369 |
| dprA | Vibrio campbellii strain DS40M4 |
38.745 |
93.448 |
0.362 |