Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT280_RS03030 Genome accession   NZ_CP118014
Coordinates   617584..618174 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-766     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 612584..623174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT280_RS03000 emrD 613066..614250 (-) 1185 WP_001349998.1 multidrug efflux MFS transporter EmrD -
  PT280_RS03005 ysdE 614332..614406 (+) 75 WP_211180519.1 protein YsdE -
  PT280_RS03010 tisB 614669..614758 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PT280_RS03015 ivbL 615323..615421 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  PT280_RS03020 ilvB 615527..617215 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  PT280_RS03025 ilvN 617219..617509 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PT280_RS03030 letA 617584..618174 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PT280_RS03035 uhpB 618174..619676 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PT280_RS03040 uhpC 619686..621005 (+) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PT280_RS03045 uhpT 621143..622534 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=720253 PT280_RS03030 WP_000633668.1 617584..618174(+) (letA) [Escherichia coli strain B-766]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=720253 PT280_RS03030 WP_000633668.1 617584..618174(+) (letA) [Escherichia coli strain B-766]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCTCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378