Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | NW977_RS05750 | Genome accession | NZ_CP102953 |
| Coordinates | 1204107..1204979 (+) | Length | 290 a.a. |
| NCBI ID | WP_000931872.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain 32-T-13 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1167226..1227769 | 1204107..1204979 | within | 0 |
Gene organization within MGE regions
Location: 1167226..1227769
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NW977_RS05585 (NW977_05585) | - | 1167533..1167736 (-) | 204 | WP_001198020.1 | TM2 domain-containing protein | - |
| NW977_RS05590 (NW977_05590) | - | 1168035..1168523 (+) | 489 | WP_000985290.1 | peptide deformylase | - |
| NW977_RS05595 (NW977_05595) | fmt | 1168516..1169451 (+) | 936 | WP_258414133.1 | methionyl-tRNA formyltransferase | - |
| NW977_RS05600 (NW977_05600) | rsmB | 1169448..1170755 (+) | 1308 | WP_258414134.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| NW977_RS05605 (NW977_05605) | rlmN | 1170758..1171852 (+) | 1095 | WP_000626897.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| NW977_RS05610 (NW977_05610) | - | 1171859..1172602 (+) | 744 | WP_000888494.1 | protein-serine/threonine phosphatase Stp1 | - |
| NW977_RS05615 (NW977_05615) | pknB | 1172599..1174593 (+) | 1995 | WP_258414135.1 | serine/threonine protein kinase Stk1 | - |
| NW977_RS05620 (NW977_05620) | rsgA | 1174821..1175696 (+) | 876 | WP_000847936.1 | ribosome small subunit-dependent GTPase A | - |
| NW977_RS05625 (NW977_05625) | rpe | 1175697..1176341 (+) | 645 | WP_000164332.1 | ribulose-phosphate 3-epimerase | - |
| NW977_RS05630 (NW977_05630) | - | 1176348..1176989 (+) | 642 | WP_000547905.1 | thiamine diphosphokinase | - |
| NW977_RS05635 (NW977_05635) | rpmB | 1177370..1177558 (-) | 189 | WP_000517908.1 | 50S ribosomal protein L28 | - |
| NW977_RS05640 (NW977_05640) | - | 1178001..1178375 (+) | 375 | WP_000171418.1 | Asp23/Gls24 family envelope stress response protein | - |
| NW977_RS05645 (NW977_05645) | fakA | 1178390..1180036 (+) | 1647 | WP_000623903.1 | fatty acid kinase catalytic subunit FakA | - |
| NW977_RS05650 (NW977_05650) | recG | 1180226..1182286 (+) | 2061 | WP_001151497.1 | ATP-dependent DNA helicase RecG | - |
| NW977_RS05655 (NW977_05655) | fapR | 1182635..1183207 (+) | 573 | WP_001548538.1 | transcription factor FapR | - |
| NW977_RS05660 (NW977_05660) | plsX | 1183212..1184198 (+) | 987 | WP_154284349.1 | phosphate acyltransferase PlsX | - |
| NW977_RS05665 (NW977_05665) | fabD | 1184191..1185117 (+) | 927 | WP_209205895.1 | ACP S-malonyltransferase | - |
| NW977_RS05670 (NW977_05670) | fabG | 1185110..1185844 (+) | 735 | WP_000167269.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| NW977_RS05675 (NW977_05675) | - | 1186347..1186580 (+) | 234 | WP_000426914.1 | acyl carrier protein | - |
| NW977_RS05680 (NW977_05680) | rnc | 1186696..1187427 (+) | 732 | WP_000043237.1 | ribonuclease III | - |
| NW977_RS05685 (NW977_05685) | smc | 1187574..1191140 (+) | 3567 | WP_258414136.1 | chromosome segregation protein SMC | - |
| NW977_RS05690 (NW977_05690) | ftsY | 1191140..1192390 (+) | 1251 | WP_000007687.1 | signal recognition particle-docking protein FtsY | - |
| NW977_RS05695 (NW977_05695) | - | 1192377..1192709 (+) | 333 | WP_000531320.1 | putative DNA-binding protein | - |
| NW977_RS05700 (NW977_05700) | ffh | 1192735..1194102 (+) | 1368 | WP_258414137.1 | signal recognition particle protein | - |
| NW977_RS05705 (NW977_05705) | rpsP | 1194537..1194812 (+) | 276 | WP_000268754.1 | 30S ribosomal protein S16 | - |
| NW977_RS05710 (NW977_05710) | rimM | 1195000..1195503 (+) | 504 | WP_001261987.1 | ribosome maturation factor RimM | - |
| NW977_RS05715 (NW977_05715) | trmD | 1195503..1196240 (+) | 738 | WP_000687328.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| NW977_RS05720 (NW977_05720) | rplS | 1196343..1196693 (+) | 351 | WP_000181404.1 | 50S ribosomal protein L19 | - |
| NW977_RS05725 (NW977_05725) | yfhO | 1196936..1199542 (-) | 2607 | WP_258414138.1 | lipoteichoic acid-specific glycosyltransferase YfhO | - |
| NW977_RS05730 (NW977_05730) | ylqF | 1199943..1200827 (+) | 885 | WP_000236722.1 | ribosome biogenesis GTPase YlqF | - |
| NW977_RS05735 (NW977_05735) | - | 1200811..1201578 (+) | 768 | WP_000176393.1 | ribonuclease HII | - |
| NW977_RS05740 (NW977_05740) | sucC | 1201687..1202853 (+) | 1167 | WP_001020801.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| NW977_RS05745 (NW977_05745) | sucD | 1202875..1203783 (+) | 909 | WP_000110251.1 | succinate--CoA ligase subunit alpha | - |
| NW977_RS05750 (NW977_05750) | dprA | 1204107..1204979 (+) | 873 | WP_000931872.1 | DNA-processing protein DprA | Machinery gene |
| NW977_RS05755 (NW977_05755) | topA | 1205153..1207228 (+) | 2076 | WP_001557331.1 | type I DNA topoisomerase | - |
| NW977_RS05760 (NW977_05760) | trmFO | 1207384..1208691 (+) | 1308 | WP_000195259.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| NW977_RS05765 (NW977_05765) | xerC | 1209108..1210004 (+) | 897 | WP_001015598.1 | tyrosine recombinase XerC | - |
| NW977_RS05770 (NW977_05770) | hslV | 1210001..1210546 (+) | 546 | WP_000072681.1 | ATP-dependent protease subunit HslV | - |
| NW977_RS05775 (NW977_05775) | hslU | 1210612..1212015 (+) | 1404 | WP_000379054.1 | ATP-dependent protease ATPase subunit HslU | - |
| NW977_RS05780 (NW977_05780) | codY | 1212040..1212813 (+) | 774 | WP_000055337.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| NW977_RS05785 (NW977_05785) | - | 1212864..1212956 (+) | 93 | WP_031788481.1 | hypothetical protein | - |
| NW977_RS05790 (NW977_05790) | rpsB | 1213155..1213922 (+) | 768 | WP_000268484.1 | 30S ribosomal protein S2 | - |
| NW977_RS05795 (NW977_05795) | - | 1213956..1214069 (+) | 114 | WP_001789890.1 | hypothetical protein | - |
| NW977_RS05800 (NW977_05800) | tsf | 1214104..1214985 (+) | 882 | WP_072497235.1 | translation elongation factor Ts | - |
| NW977_RS05805 (NW977_05805) | pyrH | 1215122..1215844 (+) | 723 | WP_000057330.1 | UMP kinase | - |
| NW977_RS05810 (NW977_05810) | frr | 1215863..1216417 (+) | 555 | WP_001280006.1 | ribosome recycling factor | - |
| NW977_RS05815 (NW977_05815) | - | 1216790..1217560 (+) | 771 | WP_000473705.1 | isoprenyl transferase | - |
| NW977_RS05820 (NW977_05820) | - | 1217567..1218349 (+) | 783 | WP_000868413.1 | phosphatidate cytidylyltransferase | - |
| NW977_RS05825 (NW977_05825) | rseP | 1218561..1219847 (+) | 1287 | WP_000121122.1 | RIP metalloprotease RseP | - |
| NW977_RS05830 (NW977_05830) | - | 1219867..1221570 (+) | 1704 | WP_000814094.1 | proline--tRNA ligase | - |
| NW977_RS05835 (NW977_05835) | - | 1221834..1226144 (+) | 4311 | WP_258414155.1 | PolC-type DNA polymerase III | - |
| NW977_RS05840 (NW977_05840) | rimP | 1226434..1226901 (+) | 468 | WP_000036631.1 | ribosome maturation factor RimP | - |
Sequence
Protein
Download Length: 290 a.a. Molecular weight: 33212.51 Da Isoelectric Point: 8.3112
>NTDB_id=720245 NW977_RS05750 WP_000931872.1 1204107..1204979(+) (dprA) [Staphylococcus aureus strain 32-T-13]
MLNHILLKLIWSRFTTAQIHLLLKTFPSCCEVDEYERMHILENFCKLLADKKIDAKVNRYKEISVDEIETTIQKTQLNYI
TCFDHNYPYLLKETYNYPIILFYKGNINLLSYPHTLAVVGSRLSGDYTLKALNHLFVSFQQMSFCVVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
MLNHILLKLIWSRFTTAQIHLLLKTFPSCCEVDEYERMHILENFCKLLADKKIDAKVNRYKEISVDEIETTIQKTQLNYI
TCFDHNYPYLLKETYNYPIILFYKGNINLLSYPHTLAVVGSRLSGDYTLKALNHLFVSFQQMSFCVVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
Nucleotide
Download Length: 873 bp
>NTDB_id=720245 NW977_RS05750 WP_000931872.1 1204107..1204979(+) (dprA) [Staphylococcus aureus strain 32-T-13]
ATGTTAAATCACATTTTACTTAAATTAATTTGGAGTCGTTTTACTACTGCACAAATACATCTACTTTTAAAAACTTTTCC
AAGTTGTTGTGAAGTAGATGAATATGAACGAATGCATATTCTAGAAAATTTTTGTAAGCTTTTAGCGGATAAAAAAATAG
ATGCTAAAGTTAACCGTTACAAGGAAATTTCTGTTGATGAAATTGAAACAACAATTCAGAAAACCCAATTAAATTATATA
ACTTGTTTTGATCATAATTATCCCTATTTATTAAAAGAAACTTACAATTATCCTATCATTTTGTTCTATAAAGGGAATAT
TAACCTCCTTAGTTATCCGCACACTTTAGCTGTCGTTGGGTCACGATTATCAGGCGACTATACTTTAAAGGCATTGAATC
ATCTCTTCGTTTCATTTCAACAAATGAGTTTCTGTGTTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
ATGTTAAATCACATTTTACTTAAATTAATTTGGAGTCGTTTTACTACTGCACAAATACATCTACTTTTAAAAACTTTTCC
AAGTTGTTGTGAAGTAGATGAATATGAACGAATGCATATTCTAGAAAATTTTTGTAAGCTTTTAGCGGATAAAAAAATAG
ATGCTAAAGTTAACCGTTACAAGGAAATTTCTGTTGATGAAATTGAAACAACAATTCAGAAAACCCAATTAAATTATATA
ACTTGTTTTGATCATAATTATCCCTATTTATTAAAAGAAACTTACAATTATCCTATCATTTTGTTCTATAAAGGGAATAT
TAACCTCCTTAGTTATCCGCACACTTTAGCTGTCGTTGGGTCACGATTATCAGGCGACTATACTTTAAAGGCATTGAATC
ATCTCTTCGTTTCATTTCAACAAATGAGTTTCTGTGTTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
65.677 |
100 |
0.686 |
| dprA | Staphylococcus aureus N315 |
66.897 |
100 |
0.669 |
| dprA | Lactococcus lactis subsp. cremoris KW2 |
38.214 |
96.552 |
0.369 |
| dprA | Vibrio campbellii strain DS40M4 |
38.745 |
93.448 |
0.362 |