Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   NW338_RS09530 Genome accession   NZ_CP102945
Coordinates   1933254..1934297 (-) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus aureus strain SCAID OTT1-2022 (150)     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928254..1939297
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NW338_RS09500 (NW338_09500) - 1928676..1929932 (-) 1257 WP_072398252.1 aminopeptidase -
  NW338_RS09505 (NW338_09505) - 1929935..1930135 (-) 201 WP_000180460.1 DUF1128 family protein -
  NW338_RS09510 (NW338_09510) - 1930282..1930746 (+) 465 WP_000567539.1 low molecular weight protein-tyrosine-phosphatase -
  NW338_RS09515 (NW338_09515) - 1930753..1931028 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  NW338_RS09520 (NW338_09520) - 1931306..1932523 (+) 1218 WP_000037078.1 YihY/virulence factor BrkB family protein -
  NW338_RS09525 (NW338_09525) vraR 1932635..1933264 (-) 630 WP_000153532.1 two-component system response regulator VraR Regulator
  NW338_RS09530 (NW338_09530) vraS 1933254..1934297 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  NW338_RS09535 (NW338_09535) liaF 1934294..1934995 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  NW338_RS09540 (NW338_09540) - 1935010..1935396 (-) 387 WP_001110179.1 hypothetical protein -
  NW338_RS09545 (NW338_09545) map 1935613..1936371 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  NW338_RS09550 (NW338_09550) - 1936843..1937829 (+) 987 WP_000999713.1 aromatic acid exporter family protein -
  NW338_RS09555 (NW338_09555) - 1938260..1938673 (-) 414 WP_025175030.1 hypothetical protein -
  NW338_RS09560 (NW338_09560) - 1938702..1938812 (-) 111 WP_001790257.1 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=720092 NW338_RS09530 WP_001017131.1 1933254..1934297(-) (vraS) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=720092 NW338_RS09530 WP_001017131.1 1933254..1934297(-) (vraS) [Staphylococcus aureus strain SCAID OTT1-2022 (150)]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1