Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT288_RS13095 Genome accession   NZ_CP117960
Coordinates   2695704..2696294 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-3008     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2690704..2701294
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT288_RS13060 yidF 2690820..2691317 (+) 498 WP_000148063.1 radical SAM protein -
  PT288_RS13065 emrD 2691325..2692509 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PT288_RS13070 ysdE 2692591..2692665 (+) 75 WP_211180519.1 protein YsdE -
  PT288_RS13075 tisB 2692789..2692878 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PT288_RS13080 ivbL 2693443..2693541 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PT288_RS13085 ilvB 2693647..2695335 (+) 1689 WP_000168464.1 acetolactate synthase large subunit -
  PT288_RS13090 ilvN 2695339..2695629 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PT288_RS13095 letA 2695704..2696294 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PT288_RS13100 uhpB 2696294..2697796 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PT288_RS13105 uhpC 2697806..2699125 (+) 1320 WP_000936560.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PT288_RS13110 uhpT 2699263..2700654 (+) 1392 WP_000879202.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=719762 PT288_RS13095 WP_000633668.1 2695704..2696294(+) (letA) [Escherichia coli strain B-3008]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=719762 PT288_RS13095 WP_000633668.1 2695704..2696294(+) (letA) [Escherichia coli strain B-3008]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378