Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT284_RS19465 Genome accession   NZ_CP117959
Coordinates   3853137..3853727 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-2207     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3848137..3858727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT284_RS19450 uhpT 3848777..3850168 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PT284_RS19455 uhpC 3850306..3851625 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PT284_RS19460 uhpB 3851635..3853137 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PT284_RS19465 letA 3853137..3853727 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PT284_RS19470 ilvN 3853803..3854093 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PT284_RS19475 ilvB 3854097..3855785 (-) 1689 WP_078046114.1 acetolactate synthase large subunit -
  PT284_RS19480 ivbL 3855891..3855989 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PT284_RS19485 tisB 3856554..3856643 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  PT284_RS19490 ysdE 3856767..3856841 (-) 75 WP_211180519.1 protein YsdE -
  PT284_RS19495 emrD 3856923..3858107 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PT284_RS19500 yidF 3858115..3858612 (-) 498 WP_078046115.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=719693 PT284_RS19465 WP_000633668.1 3853137..3853727(-) (letA) [Escherichia coli strain B-2207]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=719693 PT284_RS19465 WP_000633668.1 3853137..3853727(-) (letA) [Escherichia coli strain B-2207]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378