Detailed information NTG0071958

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EL263_RS09155
• Genome accession: NZ_AP018938
• Coordinates: 1723327..1724394 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain ATCC 49619
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1718327..1729394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL263_RS09135 (SPAT_1733)	treR	1720124..1720834 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EL263_RS09145	-	1720989..1722315 (+)	1327	Protein_1734	ISL3 family transposase	-
EL263_RS09150 (SPAT_1737)	amiF	1722390..1723316 (-)	927	WP_044812815.1	ATP-binding cassette domain-containing protein	Regulator
EL263_RS09155 (SPAT_1738)	amiE	1723327..1724394 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
EL263_RS09160 (SPAT_1739)	amiD	1724403..1725329 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
EL263_RS09165 (SPAT_1740)	amiC	1725329..1726825 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
EL263_RS09170 (SPAT_1741)	amiA3	1726892..1728889 (-)	1998	WP_114880767.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=71958 EL263_RS09155 WP_000159553.1 1723327..1724394(-) (amiE) [Streptococcus pneumoniae strain ATCC 49619]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=71958 EL263_RS09155 WP_000159553.1 1723327..1724394(-) (amiE) [Streptococcus pneumoniae strain ATCC 49619]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACTGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541