Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NWE23_RS07685 Genome accession   NZ_CP102746
Coordinates   1548829..1549518 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain Transconjugant cAKJ47-2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1543829..1554518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE23_RS07660 (NWE23_07670) - 1544300..1545012 (-) 713 Protein_1466 NADPH-dependent oxidoreductase -
  NWE23_RS07665 (NWE23_07675) dnaI 1545009..1545908 (-) 900 WP_012027642.1 primosomal protein DnaI -
  NWE23_RS07670 (NWE23_07680) - 1545908..1547059 (-) 1152 WP_012027643.1 replication initiation/membrane attachment protein -
  NWE23_RS07675 (NWE23_07685) nrdR 1547046..1547537 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  NWE23_RS07680 (NWE23_07690) - 1547609..1548739 (-) 1131 WP_012027644.1 AI-2E family transporter -
  NWE23_RS07685 (NWE23_07695) covR 1548829..1549518 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  NWE23_RS07690 (NWE23_07700) gndA 1549600..1551027 (-) 1428 WP_012028448.1 NADP-dependent phosphogluconate dehydrogenase -
  NWE23_RS07695 (NWE23_07705) - 1551124..1551663 (-) 540 WP_012027649.1 DUF177 domain-containing protein -
  NWE23_RS07700 (NWE23_07710) trxB 1551673..1552590 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  NWE23_RS07705 (NWE23_07715) - 1552604..1552828 (-) 225 WP_002936682.1 DUF4059 family protein -
  NWE23_RS07710 (NWE23_07720) - 1552846..1554189 (-) 1344 WP_012027650.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=718659 NWE23_RS07685 WP_012027645.1 1548829..1549518(-) (covR) [Streptococcus suis strain Transconjugant cAKJ47-2]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=718659 NWE23_RS07685 WP_012027645.1 1548829..1549518(-) (covR) [Streptococcus suis strain Transconjugant cAKJ47-2]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAAAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTGGTGAAGCCCTTTGTCAT
TAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGCTGGCAACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432