Detailed information NTG0071817

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EL277_RS10240
• Genome accession: NZ_AP018936
• Coordinates: 1921717..1922727 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain NU83127
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1916717..1927727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL277_RS10215 (SPNU_1931)	-	1917702..1917996 (-)	295	Protein_1903	hypothetical protein	-
EL277_RS10220 (SPNU_1932)	-	1918158..1918610 (+)	453	WP_000079148.1	universal stress protein	-
EL277_RS10225 (SPNU_1933)	-	1918645..1920033 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EL277_RS10230 (SPNU_1934)	-	1920099..1921061 (+)	963	WP_001124777.1	asparaginase	-
EL277_RS10235 (SPNU_1935)	-	1921090..1921653 (-)	564	WP_001092024.1	hypothetical protein	-
EL277_RS10240 (SPNU_1936)	ccpA	1921717..1922727 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EL277_RS10245 (SPNU_1937)	-	1923152..1923751 (-)	600	WP_000866703.1	response regulator transcription factor	-
EL277_RS10250 (SPNU_1938)	-	1923752..1924849 (-)	1098	WP_000893503.1	sensor histidine kinase	-
EL277_RS10255 (SPNU_1939)	-	1924849..1925586 (-)	738	WP_000832915.1	ABC transporter permease	-
EL277_RS10260 (SPNU_1940)	-	1925588..1926472 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EL277_RS10265 (SPNU_1941)	-	1926459..1926653 (-)	195	WP_000820189.1	hypothetical protein	-
EL277_RS12440	-	1926650..1926856 (-)	207	Protein_1914	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=71817 EL277_RS10240 WP_000990607.1 1921717..1922727(-) (ccpA) [Streptococcus pneumoniae strain NU83127]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=71817 EL277_RS10240 WP_000990607.1 1921717..1922727(-) (ccpA) [Streptococcus pneumoniae strain NU83127]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568