Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   MGCS35823_RS02810 Genome accession   NZ_CP117289
Coordinates   523003..523827 (+) Length   274 a.a.
NCBI ID   WP_275910586.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 518003..528827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35823_RS02795 (MGCS35823_01136) - 520415..521165 (+) 751 Protein_494 response regulator transcription factor -
  MGCS35823_RS02805 (MGCS35823_01140) - 521507..522640 (-) 1134 WP_275902597.1 ISAs1-like element IS1548 family transposase -
  MGCS35823_RS02810 (MGCS35823_01142) comD/blpH 523003..523827 (+) 825 WP_275910586.1 GHKL domain-containing protein Regulator
  MGCS35823_RS02815 (MGCS35823_01144) - 523975..524100 (-) 126 WP_011017462.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  MGCS35823_RS02820 (MGCS35823_01148) - 524177..525541 (-) 1365 WP_084916305.1 bacteriocin secretion accessory protein -
  MGCS35823_RS02825 (MGCS35823_01150) comA/nlmT 525552..527705 (-) 2154 WP_084916306.1 peptide cleavage/export ABC transporter Regulator
  MGCS35823_RS02830 (MGCS35823_01152) - 527992..528219 (+) 228 WP_002992018.1 Blp family class II bacteriocin -
  MGCS35823_RS02835 (MGCS35823_01154) - 528232..528432 (+) 201 WP_003060803.1 class IIb bacteriocin, lactobin A/cerein 7B family -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 31596.94 Da        Isoelectric Point: 6.1352

>NTDB_id=717804 MGCS35823_RS02810 WP_275910586.1 523003..523827(+) (comD/blpH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
MILYFITIPMIDFIEEVENINFTHYQEMITAIYFLLFICFVNLLDRNLRQELQKQVVLQKELQLQNMARYSKQIEGLYQN
IRSFRHDYANILTSLKIGIDCKDIEMISSIYHKVLKDSGKVLRGEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSI
EIGEPISIKNIELIDFLTLVSILIDNAIEGAAESGIVLCFFEQFGKQILIVQNDTFEKQINLSTIFERGVSSKGNNRGVG
LSNVREILESYPTVTLKTVSNHFVFKQILEIEIL

Nucleotide


Download         Length: 825 bp        

>NTDB_id=717804 MGCS35823_RS02810 WP_275910586.1 523003..523827(+) (comD/blpH) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35823]
ATGATATTGTACTTTATTACCATTCCAATGATAGATTTTATCGAAGAAGTTGAAAATATTAATTTTACGCACTATCAAGA
GATGATAACAGCAATTTATTTTCTTTTATTTATTTGTTTTGTAAATTTATTGGATCGGAACTTACGCCAAGAATTACAAA
AGCAAGTTGTTCTACAAAAAGAGTTACAATTACAGAATATGGCTCGCTATAGTAAGCAAATCGAAGGACTGTATCAAAAT
ATCAGAAGTTTTAGACATGATTATGCAAATATTTTAACAAGCTTGAAAATAGGCATTGATTGCAAAGATATTGAAATGAT
TTCAAGCATTTATCATAAGGTGTTGAAAGATTCAGGGAAGGTTTTAAGGGGAGAAAAATTCAATCTAGCAAGGCTGAGAA
ATATAAACGACCTTCCTCTGAAAAGTTTACTGTTTGTAAAATTATCAGAAGCTCAACGCTTATCCATACCTGTATCTATA
GAAATTGGGGAACCGATTTCTATAAAAAACATTGAGTTAATCGATTTTTTAACCCTTGTTTCTATCTTGATAGATAATGC
AATCGAAGGTGCAGCAGAGTCGGGGATAGTTCTTTGTTTTTTTGAACAATTTGGTAAACAGATATTAATTGTTCAAAATG
ATACTTTTGAAAAACAGATTAATCTTTCCACGATTTTTGAGCGAGGTGTTTCTTCAAAAGGAAATAATAGGGGAGTTGGT
TTATCAAATGTTAGGGAGATATTAGAATCATATCCCACTGTTACCCTCAAAACAGTAAGTAATCATTTTGTTTTTAAACA
GATTCTAGAAATAGAAATCCTATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(172-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

42.909

100

0.431
  comD/comD2 Streptococcus equinus JB1

36.861

100

0.369