Detailed information NTG0717677

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: MGCS35957_RS00745
• Genome accession: NZ_CP117288
• Coordinates: 123827..124267 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118827..129267

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS35957_RS00715 (MGCS35957_00294)	-	120508..120873 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGCS35957_RS00720 (MGCS35957_00296)	comGA/cglA	120954..121895 (+)	942	WP_014611930.1	competence type IV pilus ATPase ComGA	Machinery gene
MGCS35957_RS00725 (MGCS35957_00298)	comGB	121831..122862 (+)	1032	Protein_107	competence type IV pilus assembly protein ComGB	-
MGCS35957_RS00730 (MGCS35957_00300)	comGC	122864..123190 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
MGCS35957_RS00735 (MGCS35957_00302)	comGD	123165..123593 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
MGCS35957_RS00740 (MGCS35957_00304)	comGE	123601..123846 (+)	246	WP_049519695.1	competence type IV pilus minor pilin ComGE	Machinery gene
MGCS35957_RS00745 (MGCS35957_00306)	comGF	123827..124267 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGCS35957_RS00750 (MGCS35957_00308)	comGG	124290..124619 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
MGCS35957_RS00755 (MGCS35957_00310)	comGH	124682..125635 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGCS35957_RS00760 (MGCS35957_00312)	-	125694..126890 (+)	1197	WP_084916957.1	acetate kinase	-
MGCS35957_RS00765 (MGCS35957_00314)	-	127197..127403 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
MGCS35957_RS00770 (MGCS35957_00316)	-	127506..128186 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
MGCS35957_RS00775 (MGCS35957_00318)	-	128204..128641 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=717677 MGCS35957_RS00745 WP_003061780.1 123827..124267(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=717677 MGCS35957_RS00745 WP_003061780.1 123827..124267(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35957]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411