Detailed information NTG0717259

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: MGCS36089_RS00810
• Genome accession: NZ_CP117284
• Coordinates: 129699..130139 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 124699..135139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36089_RS00780 (MGCS36089_00318)	-	126380..126745 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGCS36089_RS00785 (MGCS36089_00320)	comGA/cglA	126826..127767 (+)	942	WP_275926236.1	competence type IV pilus ATPase ComGA	Machinery gene
MGCS36089_RS00790 (MGCS36089_00322)	comGB	127703..128734 (+)	1032	WP_084916952.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGCS36089_RS00795 (MGCS36089_00324)	comGC	128736..129062 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
MGCS36089_RS00800 (MGCS36089_00326)	comGD	129037..129465 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
MGCS36089_RS00805 (MGCS36089_00328)	comGE	129473..129718 (+)	246	WP_049519695.1	competence type IV pilus minor pilin ComGE	Machinery gene
MGCS36089_RS00810 (MGCS36089_00330)	comGF	129699..130139 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGCS36089_RS00815 (MGCS36089_00332)	comGG	130162..130491 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
MGCS36089_RS00820 (MGCS36089_00334)	comGH	130554..131507 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGCS36089_RS00825 (MGCS36089_00336)	-	131566..132762 (+)	1197	WP_084916957.1	acetate kinase	-
MGCS36089_RS00830 (MGCS36089_00338)	-	133069..133275 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
MGCS36089_RS00835 (MGCS36089_00340)	-	133378..134058 (+)	681	WP_003060329.1	CPBP family intramembrane glutamic endopeptidase	-
MGCS36089_RS00840 (MGCS36089_00342)	-	134076..134513 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=717259 MGCS36089_RS00810 WP_003061780.1 129699..130139(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=717259 MGCS36089_RS00810 WP_003061780.1 129699..130139(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36089]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411