Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQQ28_RS00540 Genome accession   NZ_CP117235
Coordinates   29944..30534 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ATCC 25922     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 24944..35534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQQ28_RS00515 (PQQ28_00515) ysdE 25973..26047 (+) 75 WP_211180519.1 protein YsdE -
  PQQ28_RS00520 (PQQ28_00520) ivbL 26292..26390 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PQQ28_RS00525 (PQQ28_00525) ilvB 26496..28184 (+) 1689 WP_000168476.1 acetolactate synthase large subunit -
  PQQ28_RS00530 (PQQ28_00530) ilvN 28188..28478 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PQQ28_RS00535 (PQQ28_00535) - 28669..29529 (-) 861 WP_001259006.1 DUF6708 domain-containing protein -
  PQQ28_RS00540 (PQQ28_00540) letA 29944..30534 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PQQ28_RS00545 (PQQ28_00545) uhpB 30534..32036 (+) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PQQ28_RS00550 (PQQ28_00550) uhpC 32046..33365 (+) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PQQ28_RS00555 (PQQ28_00555) uhpT 33503..34894 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=716984 PQQ28_RS00540 WP_000633668.1 29944..30534(+) (letA) [Escherichia coli strain ATCC 25922]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=716984 PQQ28_RS00540 WP_000633668.1 29944..30534(+) (letA) [Escherichia coli strain ATCC 25922]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGTTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378