Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQS35_RS18540 Genome accession   NZ_CP117044
Coordinates   3807929..3808519 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-DolR     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3802929..3813519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQS35_RS18525 uhpT 3803569..3804960 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PQS35_RS18530 uhpC 3805098..3806417 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PQS35_RS18535 uhpB 3806427..3807929 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PQS35_RS18540 letA 3807929..3808519 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PQS35_RS18545 ilvN 3808594..3808884 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PQS35_RS18550 ilvB 3808888..3810576 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PQS35_RS18555 ivbL 3810682..3810780 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PQS35_RS18560 tisB 3811345..3811434 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PQS35_RS18565 ysdE 3811558..3811632 (-) 75 WP_211180519.1 protein YsdE -
  PQS35_RS18570 emrD 3811714..3812898 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PQS35_RS18575 yidF 3812906..3813403 (-) 498 WP_000148063.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=716623 PQS35_RS18540 WP_000633668.1 3807929..3808519(-) (letA) [Escherichia coli strain B-DolR]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=716623 PQS35_RS18540 WP_000633668.1 3807929..3808519(-) (letA) [Escherichia coli strain B-DolR]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378