Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQS36_RS18465 Genome accession   NZ_CP117043
Coordinates   3798886..3799476 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B-RalR     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3793886..3804476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQS36_RS18450 uhpT 3794526..3795917 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PQS36_RS18455 uhpC 3796055..3797374 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PQS36_RS18460 uhpB 3797384..3798886 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PQS36_RS18465 letA 3798886..3799476 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PQS36_RS18470 ilvN 3799551..3799841 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PQS36_RS18475 ilvB 3799845..3801533 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PQS36_RS18480 ivbL 3801639..3801737 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PQS36_RS18485 tisB 3802302..3802391 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PQS36_RS18490 ysdE 3802515..3802589 (-) 75 WP_211180519.1 protein YsdE -
  PQS36_RS18495 emrD 3802671..3803855 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PQS36_RS18500 yidF 3803863..3804360 (-) 498 WP_000148063.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=716541 PQS36_RS18465 WP_000633668.1 3798886..3799476(-) (letA) [Escherichia coli strain B-RalR]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=716541 PQS36_RS18465 WP_000633668.1 3798886..3799476(-) (letA) [Escherichia coli strain B-RalR]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGTCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378