Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL414_RS00675 Genome accession   NZ_CP117013
Coordinates   36826..37416 (+) Length   196 a.a.
NCBI ID   WP_000633667.1    Uniprot ID   -
Organism   Escherichia coli strain MLI114     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 31826..42416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL414_RS00660 (NL414_000660) ilvN 33145..33435 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NL414_RS00665 (NL414_000665) - 34510..34992 (+) 483 WP_032159284.1 hypothetical protein -
  NL414_RS00670 (NL414_000670) - 35405..36664 (+) 1260 WP_227467295.1 hypothetical protein -
  NL414_RS00675 (NL414_000675) letA 36826..37416 (+) 591 WP_000633667.1 transcriptional regulator UhpA Regulator
  NL414_RS00680 (NL414_000680) uhpB 37416..38918 (+) 1503 WP_001469012.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NL414_RS00685 (NL414_000685) uhpC 38928..40247 (+) 1320 WP_001301991.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NL414_RS00690 (NL414_000690) uhpT 40503..41894 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20870.26 Da        Isoelectric Point: 5.9206

>NTDB_id=716053 NL414_RS00675 WP_000633667.1 36826..37416(+) (letA) [Escherichia coli strain MLI114]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELAHRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=716053 NL414_RS00675 WP_000633667.1 36826..37416(+) (letA) [Escherichia coli strain MLI114]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAGCGTTGTAGCCCTGACGA
ACTGATTGCTGCGGTGCATACGGTTGCCACAGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCACCGTATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.308

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.308

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378