Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL412_RS11390 Genome accession   NZ_CP117008
Coordinates   2183286..2183942 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI109     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2178286..2188942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL412_RS11360 (NL412_011355) dcyD 2179166..2180152 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL412_RS11365 (NL412_011360) tcyL 2180167..2180835 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL412_RS11370 (NL412_011365) tcyN 2180832..2181584 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL412_RS11375 (NL412_011370) sdiA 2181814..2182536 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  NL412_RS11380 (NL412_011375) yecF 2182603..2182827 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL412_RS11385 (NL412_011380) yecU 2182814..2182990 (-) 177 WP_000590344.1 protein YecU -
  NL412_RS26185 - 2183028..2183144 (-) 117 WP_023063716.1 hypothetical protein -
  NL412_RS11390 (NL412_011385) letA 2183286..2183942 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL412_RS11395 (NL412_011390) uvrC 2183939..2185771 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NL412_RS11400 (NL412_011395) pgsA 2185828..2186376 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL412_RS11420 (NL412_011415) yecA 2187026..2187691 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=715930 NL412_RS11390 WP_000611328.1 2183286..2183942(+) (letA) [Escherichia coli strain MLI109]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=715930 NL412_RS11390 WP_000611328.1 2183286..2183942(+) (letA) [Escherichia coli strain MLI109]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482