Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL408_RS00175 Genome accession   NZ_CP116987
Coordinates   33144..33734 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain MLI107     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28144..38734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL408_RS00145 (NL408_000145) emrD 28627..29811 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  NL408_RS00150 (NL408_000150) ysdE 29893..29967 (+) 75 WP_211180519.1 protein YsdE -
  NL408_RS00155 (NL408_000155) tisB 30230..30319 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  NL408_RS00160 (NL408_000160) ivbL 30884..30982 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  NL408_RS00165 (NL408_000165) ilvB 31088..32776 (+) 1689 WP_097446414.1 acetolactate synthase large subunit -
  NL408_RS00170 (NL408_000170) ilvN 32780..33070 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NL408_RS00175 (NL408_000175) letA 33144..33734 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NL408_RS00180 (NL408_000180) uhpB 33734..35236 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NL408_RS00185 (NL408_000185) uhpC 35246..36565 (+) 1320 WP_097446413.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NL408_RS00190 (NL408_000190) uhpT 36703..38094 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=715567 NL408_RS00175 WP_000633668.1 33144..33734(+) (letA) [Escherichia coli strain MLI107]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=715567 NL408_RS00175 WP_000633668.1 33144..33734(+) (letA) [Escherichia coli strain MLI107]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378