Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PQP10_RS14130 Genome accession   NZ_CP116976
Coordinates   2933265..2933855 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CUVM53     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2928265..2938855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQP10_RS14115 (PQP10_14115) uhpT 2928905..2930296 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PQP10_RS14120 (PQP10_14120) uhpC 2930434..2931753 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PQP10_RS14125 (PQP10_14125) uhpB 2931763..2933265 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PQP10_RS14130 (PQP10_14130) letA 2933265..2933855 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PQP10_RS14135 (PQP10_14135) ilvN 2933930..2934220 (-) 291 WP_001181705.1 acetolactate synthase small subunit -
  PQP10_RS14140 (PQP10_14140) ilvB 2934224..2935912 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PQP10_RS14145 (PQP10_14145) ivbL 2936018..2936116 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PQP10_RS14150 (PQP10_14150) tisB 2936681..2936770 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PQP10_RS14155 (PQP10_14155) ysdE 2936894..2936968 (-) 75 WP_211180519.1 protein YsdE -
  PQP10_RS14160 (PQP10_14160) emrD 2937050..2938234 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PQP10_RS14165 (PQP10_14165) yidF 2938242..2938739 (-) 498 WP_000148063.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=715451 PQP10_RS14130 WP_000633668.1 2933265..2933855(-) (letA) [Escherichia coli strain CUVM53]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=715451 PQP10_RS14130 WP_000633668.1 2933265..2933855(-) (letA) [Escherichia coli strain CUVM53]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378