Detailed information NTG0715212

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: M0P24_RS11385
• Genome accession: NZ_CP116957
• Coordinates: 2222516..2225086 (-)
• Length: 856 a.a.
• NCBI ID: WP_013852331.1
• Uniprot ID: F5X3U0
• Organism: Streptococcus pasteurianus strain WUSP070
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2217516..2230086

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0P24_RS11355 (M0P24_11355)	-	2218025..2218327 (-)	303	WP_230321699.1	hypothetical protein	-
M0P24_RS11360 (M0P24_11360)	-	2218397..2218567 (-)	171	WP_231729898.1	hypothetical protein	-
M0P24_RS11365 (M0P24_11365)	-	2218628..2218804 (-)	177	WP_230321700.1	hypothetical protein	-
M0P24_RS11370 (M0P24_11370)	-	2218951..2219802 (+)	852	WP_013852329.1	helix-turn-helix domain-containing protein	-
M0P24_RS11375 (M0P24_11375)	ruvA	2219882..2220475 (-)	594	WP_003066922.1	Holliday junction branch migration protein RuvA	Machinery gene
M0P24_RS11380 (M0P24_11380)	hexB	2220477..2222399 (-)	1923	WP_111718472.1	DNA mismatch repair endonuclease MutL	Machinery gene
M0P24_RS11385 (M0P24_11385)	hexA	2222516..2225086 (-)	2571	WP_013852331.1	DNA mismatch repair protein MutS	Machinery gene
M0P24_RS11390 (M0P24_11390)	-	2225073..2225429 (-)	357	WP_003066927.1	YlbF family regulator	-
M0P24_RS11395 (M0P24_11395)	argR	2225426..2225863 (-)	438	WP_003066930.1	arginine repressor	-
M0P24_RS11400 (M0P24_11400)	argS	2226054..2227745 (+)	1692	WP_013852332.1	arginine--tRNA ligase	-
M0P24_RS11405 (M0P24_11405)	-	2227857..2228150 (+)	294	WP_013852333.1	bacteriocin immunity protein	-
M0P24_RS11410 (M0P24_11410)	-	2228192..2229697 (-)	1506	WP_013852334.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96080.51 Da
• Isoelectric Point: 4.8579

>NTDB_id=715212 M0P24_RS11385 WP_013852331.1 2222516..2225086(-) (hexA) [Streptococcus pasteurianus strain WUSP070]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREIVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPRIKAILESFESPHLDKLVNSIDTLPELESLIRSAIDP
DAPAVITEGSIIRTGFDEILDKYRKVMREGTSWIAEVETKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKALSSVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TALSTILTHLVNVHVATLEKNGDVTFLHKIAEGPADKSYGVHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEAE
PITIKSEVAEPVAEQLSLFADDSSNQEVIKVLKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=715212 M0P24_RS11385 WP_013852331.1 2222516..2225086(-) (hexA) [Streptococcus pasteurianus strain WUSP070]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAAATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAACCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGGACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATTGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAATCGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACAG
CCTTAGAAATTTCAGCAGCTGAAAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTACACGACAAAATCTAGTTTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTGTTGCGTAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTCTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACCTTGGCACAAGTGCCAAGGATTAAGGCGATTTTAGAATCGTTTGAAA
GCCCTCACCTTGACAAGCTTGTCAATAGCATTGACACTTTGCCAGAACTAGAATCGTTGATTCGATCAGCTATTGACCCA
GATGCTCCTGCTGTTATCACAGAAGGCAGCATTATCCGTACAGGTTTTGATGAGATTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGTTGGATTGCAGAAGTTGAAACTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGATGGATACTATTTCCATGTAACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCTAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTTATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACTCGTTTGCAAGACTTGGCTA
AGGCGCTTTCAAGCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCAACATTCAAC
GATAGCCATGAGATTAAAATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACCGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATGATCATATTGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACGATCTTGACGCACCTTGTCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGGGTTCATGTTGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGTATCTTGACAAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTGGAAGCTGAG
CCAATTACTATAAAATCAGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAATCAAGA
AGTGATTAAAGTACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

3D structure

• AlphaFold DB: F5X3U0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.612	100	0.716
mutS	Pseudomonas stutzeri strain ATCC 17587	37.586	100	0.382