Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   M0P24_RS11380 Genome accession   NZ_CP116957
Coordinates   2220477..2222399 (-) Length   640 a.a.
NCBI ID   WP_111718472.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP070     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2215477..2227399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P24_RS11350 (M0P24_11350) - 2216485..2217432 (-) 948 WP_230321698.1 MFS transporter -
  M0P24_RS11355 (M0P24_11355) - 2218025..2218327 (-) 303 WP_230321699.1 hypothetical protein -
  M0P24_RS11360 (M0P24_11360) - 2218397..2218567 (-) 171 WP_231729898.1 hypothetical protein -
  M0P24_RS11365 (M0P24_11365) - 2218628..2218804 (-) 177 WP_230321700.1 hypothetical protein -
  M0P24_RS11370 (M0P24_11370) - 2218951..2219802 (+) 852 WP_013852329.1 helix-turn-helix domain-containing protein -
  M0P24_RS11375 (M0P24_11375) ruvA 2219882..2220475 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA Machinery gene
  M0P24_RS11380 (M0P24_11380) hexB 2220477..2222399 (-) 1923 WP_111718472.1 DNA mismatch repair endonuclease MutL Machinery gene
  M0P24_RS11385 (M0P24_11385) hexA 2222516..2225086 (-) 2571 WP_013852331.1 DNA mismatch repair protein MutS Machinery gene
  M0P24_RS11390 (M0P24_11390) - 2225073..2225429 (-) 357 WP_003066927.1 YlbF family regulator -
  M0P24_RS11395 (M0P24_11395) argR 2225426..2225863 (-) 438 WP_003066930.1 arginine repressor -

Sequence

Protein


Download         Length: 640 a.a.        Molecular weight: 72505.52 Da        Isoelectric Point: 5.2133

>NTDB_id=715211 M0P24_RS11380 WP_111718472.1 2220477..2222399(-) (hexB) [Streptococcus pasteurianus strain WUSP070]
MSKIIELPEVLANQISAGEVIERPASVVKELVENSIDAGSSQITIEIEEAGLKKIQVTDNGEGIAQDDVALSLHRHATSK
IKNQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENHGTLLVAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEVAFSLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPEQTSLPLKQTDLYYDKERRDFFVKSDTVEEQPVQLFNEVDKQQTSVKYAQ
RSEVDNQDDEHDNLDFKNKTKINKMIESLDNEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKYEYYREKI
GDVDSSLQQLLMPYLFEFSGADFIKLQEKMELLNQVGIYLEPYGNNTFILREHPIWMKEEEIETAVYEMCDMLLLTNEVS
VKKYRAELAIMMSCKRSIKANHILDDYSARHLLVQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1923 bp        

>NTDB_id=715211 M0P24_RS11380 WP_111718472.1 2220477..2222399(-) (hexB) [Streptococcus pasteurianus strain WUSP070]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCTAACCAAATTTCAGCGGGTGAAGTTATTGAACGACCAGCTAGCGT
TGTCAAAGAATTGGTGGAAAATTCGATTGATGCAGGGAGCAGCCAAATCACCATTGAAATTGAAGAAGCTGGTTTAAAGA
AAATTCAAGTGACAGATAATGGCGAAGGAATTGCTCAAGATGATGTTGCATTAAGTTTGCACCGCCATGCCACAAGTAAA
ATTAAAAATCAAGCTGACCTTTTCCGTATTAGGACGTTAGGTTTTCGTGGTGAAGCGATACCGTCAATTGCCTCCATTAG
TCATTTTACAGTCAAAACAGCAACGGCAGATGAAAATCATGGAACATTGCTAGTAGCCAAAGGTGGTGAAATCGAAAAAC
AAGAACCGATTTCTACACCCGTTGGAACCAAAATTACGGTTGAAAATCTCTTTTATAATACGCCAGCACGTCTTAAATAC
ATGAAAAGTCTCCAATCCGAATTAGCTCATATTGTTGATGTGGTGAATCGTTTGAGTTTGGCGCACCCAGAGGTGGCTTT
TAGCTTGATTAATGATGGTCGTCAAATGACAACAACATCTGGTACTGGTGATTTGCGACAAGCAATTGCTGGTATTTATG
GGCTTAATACGGCTAAAAAAATGATTGAGATTTCGAATGCTGACCTCGATTTTGAAGTGTCTGGTTACATTAGTCTGCCA
GAATTGACACGAGCGAACCGAAACTATATTACGATTTTGATTAACGGTCGTTATATTAAAAACTTTTTGCTCAATCGTGC
GATTTTGGACGGTTATGGTTCAAAATTGATGGTGGGACGTTTTCCGATTGCTGTTATCGACATTCAAATCGACCCTTATT
TAGCTGATGTCAATGTTCACCCAACGAAGCAAGAAGTTCGTATTTCAAAGGAAAAAGAATTAATGAGCTTAATCAGCTCT
GCTATTGCAGAGAGTCTGCGTGAGCAAGATTTGATACCTGATGCTCTAGAAAATCTGGCGAAATCAAGCACACGTGGGCT
TCCGAAACCAGAGCAAACGAGCTTGCCGTTGAAACAAACAGATCTTTATTATGATAAAGAACGTCGTGATTTCTTTGTTA
AGTCAGATACGGTTGAAGAGCAACCAGTACAGTTATTCAATGAAGTTGACAAGCAACAAACATCAGTGAAATATGCGCAG
CGTTCCGAAGTAGATAATCAAGATGATGAACATGATAATCTCGATTTTAAAAACAAGACAAAAATCAATAAGATGATTGA
AAGTCTTGATAATGAGGAGTCATCAACTTTCCCAGAATTAGATTATTTCGGACAAATGCACGGAACGTATCTTTTTGCAC
AGGGAAATGGTGGGCTTTATATCATTGACCAACACGCTGCTCAAGAACGTGTTAAATATGAATATTATCGTGAGAAAATC
GGCGACGTTGACAGCTCTTTACAGCAGCTTCTCATGCCATACCTTTTTGAGTTTTCTGGAGCTGATTTTATTAAGTTGCA
AGAAAAAATGGAGCTGTTAAATCAAGTTGGTATTTATCTAGAACCATATGGAAACAACACTTTTATTCTCCGTGAACACC
CAATTTGGATGAAAGAAGAGGAAATTGAGACGGCTGTTTATGAGATGTGTGATATGCTGTTGTTGACAAATGAAGTATCG
GTGAAGAAATATCGTGCAGAATTGGCAATCATGATGTCATGCAAACGCTCAATCAAAGCGAATCACATTCTTGATGATTA
TTCCGCCCGACATCTTTTGGTTCAGTTATCACAATGTAAGAATCCTTATAACTGTCCACATGGACGTCCAGTTCTTGTCA
ACTTTACCAAAGCTGACATGGAAAAAATGTTCCGCCGTATTCAAGAAAATCACACAAGTTTAAGAGAGTTAGGAAAATAC
TAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(442-584)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

71.516

100

0.73