Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NQZ90_RS02935 Genome accession   NZ_CP102148
Coordinates   597384..598733 (+) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis strain DNC15     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 592384..603733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ90_RS02910 (NQZ90_02910) - 593495..594154 (-) 660 WP_029752657.1 amino acid ABC transporter permease -
  NQZ90_RS02915 (NQZ90_02915) - 594169..594867 (-) 699 WP_013730248.1 amino acid ABC transporter permease -
  NQZ90_RS02920 (NQZ90_02920) - 594882..595721 (-) 840 WP_248041110.1 transporter substrate-binding domain-containing protein -
  NQZ90_RS02925 (NQZ90_02925) - 595732..596493 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NQZ90_RS02930 (NQZ90_02930) micA 596687..597391 (+) 705 WP_002935840.1 response regulator YycF Regulator
  NQZ90_RS02935 (NQZ90_02935) micB 597384..598733 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NQZ90_RS02940 (NQZ90_02940) vicX 598740..599543 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  NQZ90_RS02945 (NQZ90_02945) vga(F) 599797..601182 (+) 1386 WP_257110346.1 ABC-F type ribosomal protection protein Vga(F) -
  NQZ90_RS02950 (NQZ90_02950) pbp2b 601274..603346 (+) 2073 WP_257110347.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=715001 NQZ90_RS02935 WP_002935841.1 597384..598733(+) (micB) [Streptococcus suis strain DNC15]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=715001 NQZ90_RS02935 WP_002935841.1 597384..598733(+) (micB) [Streptococcus suis strain DNC15]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCCCTCAATGATTTGTCTGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCACTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGGCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAGCATAAGGGTTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635