Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | NQZ94_RS00365 | Genome accession | NZ_CP102140 |
| Coordinates | 59572..60489 (+) | Length | 305 a.a. |
| NCBI ID | WP_002935296.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain DNC49 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13841..58685 | 59572..60489 | flank | 887 |
Gene organization within MGE regions
Location: 13841..60489
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NQZ94_RS00080 (NQZ94_00080) | ftsH | 13841..15811 (+) | 1971 | WP_004194314.1 | ATP-dependent zinc metalloprotease FtsH | - |
| NQZ94_RS00085 (NQZ94_00085) | comX/sigX | 16137..16607 (+) | 471 | WP_002936602.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| NQZ94_RS00190 (NQZ94_00190) | mreC | 23910..24746 (+) | 837 | WP_009908845.1 | rod shape-determining protein MreC | - |
| NQZ94_RS00195 (NQZ94_00195) | mreD | 24736..25251 (+) | 516 | WP_002935339.1 | rod shape-determining protein MreD | - |
| NQZ94_RS00200 (NQZ94_00200) | pcsB | 25336..26592 (+) | 1257 | WP_002935338.1 | peptidoglycan hydrolase PcsB | - |
| NQZ94_RS00205 (NQZ94_00205) | - | 26695..27660 (+) | 966 | WP_024409289.1 | ribose-phosphate diphosphokinase | - |
| NQZ94_RS00210 (NQZ94_00210) | - | 27751..28929 (+) | 1179 | WP_002935336.1 | pyridoxal phosphate-dependent aminotransferase | - |
| NQZ94_RS00215 (NQZ94_00215) | recO | 28916..29698 (+) | 783 | WP_002935335.1 | DNA repair protein RecO | - |
| NQZ94_RS00220 (NQZ94_00220) | plsX | 29695..30702 (+) | 1008 | WP_002935334.1 | phosphate acyltransferase PlsX | - |
| NQZ94_RS00225 (NQZ94_00225) | - | 30695..30943 (+) | 249 | WP_002935333.1 | phosphopantetheine-binding protein | - |
| NQZ94_RS00230 (NQZ94_00230) | purC | 31061..31768 (+) | 708 | WP_002935328.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| NQZ94_RS00235 (NQZ94_00235) | - | 31781..35500 (+) | 3720 | WP_009908856.1 | phosphoribosylformylglycinamidine synthase | - |
| NQZ94_RS00240 (NQZ94_00240) | purF | 35503..36957 (+) | 1455 | WP_009908857.1 | amidophosphoribosyltransferase | - |
| NQZ94_RS00245 (NQZ94_00245) | purM | 37013..38035 (+) | 1023 | WP_009908859.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| NQZ94_RS00250 (NQZ94_00250) | purN | 38032..38583 (+) | 552 | WP_009908860.1 | phosphoribosylglycinamide formyltransferase | - |
| NQZ94_RS00255 (NQZ94_00255) | purH | 38593..40140 (+) | 1548 | WP_002935323.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| NQZ94_RS00260 (NQZ94_00260) | - | 40205..41035 (+) | 831 | WP_002935322.1 | DNA adenine methylase | - |
| NQZ94_RS00265 (NQZ94_00265) | - | 41025..41840 (+) | 816 | WP_032499218.1 | site-specific DNA-methyltransferase | - |
| NQZ94_RS00270 (NQZ94_00270) | - | 41818..42744 (+) | 927 | WP_002935320.1 | type II restriction endonuclease | - |
| NQZ94_RS00275 (NQZ94_00275) | - | 42744..43649 (+) | 906 | WP_002935319.1 | type II restriction endonuclease | - |
| NQZ94_RS00280 (NQZ94_00280) | purD | 43770..45032 (+) | 1263 | WP_002935318.1 | phosphoribosylamine--glycine ligase | - |
| NQZ94_RS00285 (NQZ94_00285) | purE | 45058..45546 (+) | 489 | WP_009908864.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| NQZ94_RS00290 (NQZ94_00290) | purK | 45533..46618 (+) | 1086 | WP_002935314.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| NQZ94_RS00295 (NQZ94_00295) | - | 46605..47528 (+) | 924 | WP_002935313.1 | DUF4268 domain-containing protein | - |
| NQZ94_RS00300 (NQZ94_00300) | purB | 47563..48855 (+) | 1293 | WP_013730055.1 | adenylosuccinate lyase | - |
| NQZ94_RS00305 (NQZ94_00305) | - | 49367..50191 (+) | 825 | WP_002935311.1 | ABC transporter ATP-binding protein | - |
| NQZ94_RS00310 (NQZ94_00310) | - | 50184..50918 (+) | 735 | WP_002935310.1 | ABC transporter permease | - |
| NQZ94_RS00315 (NQZ94_00315) | - | 51253..51981 (+) | 729 | WP_002935309.1 | DUF2705 family protein | - |
| NQZ94_RS00320 (NQZ94_00320) | - | 51991..52569 (+) | 579 | WP_002935308.1 | CPBP family intramembrane glutamic endopeptidase | - |
| NQZ94_RS00325 (NQZ94_00325) | - | 52584..53012 (+) | 429 | WP_002935307.1 | Msa family membrane protein | - |
| NQZ94_RS00330 (NQZ94_00330) | - | 53005..53877 (+) | 873 | WP_002935305.1 | ABC transporter ATP-binding protein | - |
| NQZ94_RS00335 (NQZ94_00335) | - | 53883..54653 (+) | 771 | WP_002935304.1 | membrane protein | - |
| NQZ94_RS00340 (NQZ94_00340) | - | 54656..56368 (+) | 1713 | WP_002935303.1 | ABC transporter ATP-binding protein | - |
| NQZ94_RS00345 (NQZ94_00345) | - | 56470..56643 (+) | 174 | WP_002935301.1 | hypothetical protein | - |
| NQZ94_RS00350 (NQZ94_00350) | ruvB | 56938..57939 (+) | 1002 | WP_002935300.1 | Holliday junction branch migration DNA helicase RuvB | - |
| NQZ94_RS00355 (NQZ94_00355) | - | 57939..58685 (+) | 747 | WP_002935299.1 | GNAT family N-acetyltransferase | - |
| NQZ94_RS00360 (NQZ94_00360) | - | 58687..59325 (+) | 639 | WP_002935298.1 | HAD-IA family hydrolase | - |
| NQZ94_RS00365 (NQZ94_00365) | comR | 59572..60489 (+) | 918 | WP_002935296.1 | helix-turn-helix domain-containing protein | Regulator |
Sequence
Protein
Download Length: 305 a.a. Molecular weight: 36252.32 Da Isoelectric Point: 4.6744
>NTDB_id=714762 NQZ94_RS00365 WP_002935296.1 59572..60489(+) (comR) [Streptococcus suis strain DNC49]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR
Nucleotide
Download Length: 918 bp
>NTDB_id=714762 NQZ94_RS00365 WP_002935296.1 59572..60489(+) (comR) [Streptococcus suis strain DNC49]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis D9 |
100 |
100 |
1 |
| comR | Streptococcus suis P1/7 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus suis 05ZYH33 |
62.126 |
98.689 |
0.613 |
| comR | Streptococcus mutans UA159 |
37 |
98.361 |
0.364 |