Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NQZ97_RS09470 Genome accession   NZ_CP102136
Coordinates   1936426..1937718 (-) Length   430 a.a.
NCBI ID   WP_170238431.1    Uniprot ID   -
Organism   Streptococcus suis strain M105052_S26     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1931426..1942718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ97_RS09460 (NQZ97_09460) hpf 1935148..1935690 (-) 543 WP_014637536.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NQZ97_RS09465 (NQZ97_09465) - 1935768..1936433 (-) 666 WP_105130092.1 ComF family protein -
  NQZ97_RS09470 (NQZ97_09470) comFA/cflA 1936426..1937718 (-) 1293 WP_170238431.1 DEAD/DEAH box helicase Machinery gene
  NQZ97_RS09475 (NQZ97_09475) - 1937775..1938407 (+) 633 WP_170238432.1 YigZ family protein -
  NQZ97_RS09480 (NQZ97_09480) cysK 1938497..1939423 (+) 927 WP_002937015.1 cysteine synthase A -
  NQZ97_RS09485 (NQZ97_09485) - 1939450..1939821 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  NQZ97_RS09490 (NQZ97_09490) - 1939823..1941223 (-) 1401 WP_024377222.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NQZ97_RS09495 (NQZ97_09495) - 1941273..1941914 (-) 642 WP_002937025.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 49017.63 Da        Isoelectric Point: 9.0315

>NTDB_id=714645 NQZ97_RS09470 WP_170238431.1 1936426..1937718(-) (comFA/cflA) [Streptococcus suis strain M105052_S26]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAVDNAVKEDGVQVFLTATSTDEL
DKKVRMGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=714645 NQZ97_RS09470 WP_170238431.1 1936426..1937718(-) (comFA/cflA) [Streptococcus suis strain M105052_S26]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAGCTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAC
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTGGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGTAGATAATGCGGTCAAGGAAGACGGAGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAATGGGTAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCTAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGTCGGGTTGGTAGGAGTATGGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae Rx1

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae D39

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae R6

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae TIGR4

66.821

100

0.67
  comFA/cflA Streptococcus mitis SK321

66.357

100

0.665
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.283

100

0.384
  comFA Bacillus subtilis subsp. subtilis str. 168

37.831

96.512

0.365