Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   NQZ98_RS00850 Genome accession   NZ_CP102135
Coordinates   135285..135719 (+) Length   144 a.a.
NCBI ID   WP_079268055.1    Uniprot ID   -
Organism   Streptococcus suis strain M106471_S40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 136370..137233 135285..135719 flank 651


Gene organization within MGE regions


Location: 135285..137233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS00850 (NQZ98_00850) comGF/cglF 135285..135719 (+) 435 WP_079268055.1 competence type IV pilus minor pilin ComGF Machinery gene
  NQZ98_RS00855 (NQZ98_00855) comGG 135697..136224 (+) 528 WP_024399584.1 competence type IV pilus minor pilin ComGG -
  NQZ98_RS00860 (NQZ98_00860) - 136370..137233 (+) 864 WP_105141859.1 IS982 family transposase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16485.85 Da        Isoelectric Point: 8.8227

>NTDB_id=714562 NQZ98_RS00850 WP_079268055.1 135285..135719(+) (comGF/cglF) [Streptococcus suis strain M106471_S40]
MLKSKIPAFTLLECLVALVILSGSLLIFEGLSKLLVQEAHYHRQSVQKEWLVFSSQLRSEWDQSELVKVENGKVYVNKAG
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide


Download         Length: 435 bp        

>NTDB_id=714562 NQZ98_RS00850 WP_079268055.1 135285..135719(+) (comGF/cglF) [Streptococcus suis strain M106471_S40]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGCTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCACCGTCAATCTGTCCAAAAGGAGTGGCTAGTATTTT
CTAGTCAGTTGCGGTCGGAATGGGACCAGTCGGAATTAGTCAAGGTTGAAAATGGCAAGGTCTATGTCAATAAGGCTGGA
CAAGCATTAGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACCAATGATAGGGGTCAGGGCTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(37-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae TIGR4

54.61

97.917

0.535
  comGF/cglF Streptococcus pneumoniae Rx1

54.61

97.917

0.535
  comGF/cglF Streptococcus pneumoniae D39

54.61

97.917

0.535
  comGF/cglF Streptococcus pneumoniae R6

54.61

97.917

0.535
  comGF/cglF Streptococcus mitis NCTC 12261

55.224

93.056

0.514
  comYF Streptococcus mutans UA140

49.306

100

0.493
  comGF/cglF Streptococcus mitis SK321

52.239

93.056

0.486
  comYF Streptococcus mutans UA159

48.611

100

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

45.39

97.917

0.444