Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NQZ98_RS00385 Genome accession   NZ_CP102135
Coordinates   61785..62702 (+) Length   305 a.a.
NCBI ID   WP_024399971.1    Uniprot ID   A0A0Z8LAV1
Organism   Streptococcus suis strain M106471_S40     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 56785..67702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS00360 (NQZ98_00360) - 57181..57909 (+) 729 WP_024399966.1 hypothetical protein -
  NQZ98_RS00365 (NQZ98_00365) - 57935..58807 (+) 873 WP_024399967.1 ABC transporter ATP-binding protein -
  NQZ98_RS00370 (NQZ98_00370) ruvB 59148..60152 (+) 1005 WP_024399968.1 Holliday junction branch migration DNA helicase RuvB -
  NQZ98_RS00375 (NQZ98_00375) - 60152..60898 (+) 747 WP_024399969.1 GNAT family N-acetyltransferase -
  NQZ98_RS00380 (NQZ98_00380) - 60900..61538 (+) 639 WP_024399970.1 HAD-IA family hydrolase -
  NQZ98_RS00385 (NQZ98_00385) comR 61785..62702 (+) 918 WP_024399971.1 helix-turn-helix domain-containing protein Regulator
  NQZ98_RS00390 (NQZ98_00390) - 62967..64187 (+) 1221 WP_024399972.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NQZ98_RS00395 (NQZ98_00395) - 64378..65901 (+) 1524 WP_024399973.1 quinol oxidase -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 36283.34 Da        Isoelectric Point: 4.6318

>NTDB_id=714551 NQZ98_RS00385 WP_024399971.1 61785..62702(+) (comR) [Streptococcus suis strain M106471_S40]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYDHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide


Download         Length: 918 bp        

>NTDB_id=714551 NQZ98_RS00385 WP_024399971.1 61785..62702(+) (comR) [Streptococcus suis strain M106471_S40]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGTTGTAGATACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATGATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAGTATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAATTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8LAV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis D9

99.344

100

0.993
  comR Streptococcus suis P1/7

61.794

98.689

0.61
  comR Streptococcus suis 05ZYH33

61.794

98.689

0.61
  comR Streptococcus mutans UA159

37.333

98.361

0.367