Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL421_RS09010 Genome accession   NZ_CP116929
Coordinates   1830660..1831316 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI105     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1825660..1836316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL421_RS08980 (NL421_008985) dcyD 1826539..1827525 (+) 987 WP_114427772.1 D-cysteine desulfhydrase -
  NL421_RS08985 (NL421_008990) tcyL 1827540..1828208 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL421_RS08990 (NL421_008995) tcyN 1828205..1828957 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL421_RS08995 (NL421_009000) sdiA 1829187..1829909 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  NL421_RS09000 (NL421_009005) yecF 1829977..1830201 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL421_RS09005 (NL421_009010) yecU 1830188..1830364 (-) 177 WP_000590344.1 protein YecU -
  NL421_RS22640 - 1830402..1830518 (-) 117 WP_001302039.1 hypothetical protein -
  NL421_RS09010 (NL421_009015) letA 1830660..1831316 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL421_RS09015 (NL421_009020) uvrC 1831313..1833145 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NL421_RS09020 (NL421_009025) pgsA 1833202..1833750 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL421_RS09040 (NL421_009045) yecA 1834399..1835064 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=714461 NL421_RS09010 WP_000611328.1 1830660..1831316(+) (letA) [Escherichia coli strain MLI105]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=714461 NL421_RS09010 WP_000611328.1 1830660..1831316(+) (letA) [Escherichia coli strain MLI105]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482