Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL419_RS09830 Genome accession   NZ_CP116923
Coordinates   1933341..1933997 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MLI104K1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928341..1938997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL419_RS09800 (NL419_009800) dcyD 1929221..1930207 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NL419_RS09805 (NL419_009805) tcyL 1930222..1930890 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NL419_RS09810 (NL419_009810) tcyN 1930887..1931639 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NL419_RS09815 (NL419_009815) sdiA 1931869..1932591 (+) 723 WP_001154275.1 transcriptional regulator SdiA -
  NL419_RS09820 (NL419_009820) yecF 1932658..1932882 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NL419_RS09825 (NL419_009825) yecU 1932869..1933045 (-) 177 WP_032160694.1 protein YecU -
  NL419_RS09830 (NL419_009830) letA 1933341..1933997 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NL419_RS09835 (NL419_009835) uvrC 1933994..1935826 (+) 1833 WP_072667239.1 excinuclease ABC subunit UvrC Machinery gene
  NL419_RS09840 (NL419_009840) pgsA 1935883..1936431 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NL419_RS09860 (NL419_009860) yecA 1937081..1937746 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=714300 NL419_RS09830 WP_000611328.1 1933341..1933997(+) (letA) [Escherichia coli strain MLI104K1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=714300 NL419_RS09830 WP_000611328.1 1933341..1933997(+) (letA) [Escherichia coli strain MLI104K1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482