Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   NQZ84_RS02175 Genome accession   NZ_CP102094
Coordinates   434862..436154 (+) Length   430 a.a.
NCBI ID   WP_257049611.1    Uniprot ID   -
Organism   Streptococcus suis strain 12RC1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 429862..441154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS02150 (NQZ84_02150) - 430667..431308 (+) 642 WP_002937025.1 response regulator transcription factor -
  NQZ84_RS02155 (NQZ84_02155) - 431358..432758 (+) 1401 WP_044768661.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  NQZ84_RS02160 (NQZ84_02160) - 432760..433131 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  NQZ84_RS02165 (NQZ84_02165) cysK 433157..434083 (-) 927 WP_002937015.1 cysteine synthase A -
  NQZ84_RS02170 (NQZ84_02170) - 434173..434805 (-) 633 WP_015646510.1 YigZ family protein -
  NQZ84_RS02175 (NQZ84_02175) comFA/cflA 434862..436154 (+) 1293 WP_257049611.1 DEAD/DEAH box helicase Machinery gene
  NQZ84_RS02180 (NQZ84_02180) - 436147..436812 (+) 666 WP_044768663.1 ComF family protein -
  NQZ84_RS02185 (NQZ84_02185) hpf 436889..437431 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NQZ84_RS02190 (NQZ84_02190) - 437487..437690 (+) 204 WP_044768664.1 hypothetical protein -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48999.56 Da        Isoelectric Point: 9.2481

>NTDB_id=714292 NQZ84_RS02175 WP_257049611.1 434862..436154(+) (comFA/cflA) [Streptococcus suis strain 12RC1]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGITFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPYVDVFVVQANHYLYTASSLVQITGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=714292 NQZ84_RS02175 WP_257049611.1 434862..436154(+) (comFA/cflA) [Streptococcus suis strain 12RC1]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAATAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAATTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGATAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACAGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATATGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCATCAAGTCTTGTTCAGATTACAGGCCGGGTCGGAAGGAGTATAGAACGTCCGACTGGT
TTACTTCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae Rx1

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae D39

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae R6

66.125

100

0.663
  comFA/cflA Streptococcus pneumoniae TIGR4

66.125

100

0.663
  comFA/cflA Streptococcus mitis SK321

65.661

100

0.658
  comFA Lactococcus lactis subsp. cremoris KW2

53.652

92.326

0.495
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.349

96.512

0.36