Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NL419_RS00640 Genome accession   NZ_CP116923
Coordinates   33002..33592 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain MLI104K1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28002..38592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NL419_RS00605 (NL419_000605) yidF 28119..28616 (+) 498 WP_000148061.1 radical SAM protein -
  NL419_RS00610 (NL419_000610) emrD 28624..29808 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  NL419_RS00615 (NL419_000615) ysdE 29890..29964 (+) 75 WP_211180519.1 protein YsdE -
  NL419_RS00620 (NL419_000620) tisB 30088..30177 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  NL419_RS00625 (NL419_000625) ivbL 30741..30839 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  NL419_RS00630 (NL419_000630) ilvB 30945..32633 (+) 1689 WP_021570996.1 acetolactate synthase large subunit -
  NL419_RS00635 (NL419_000635) ilvN 32637..32927 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  NL419_RS00640 (NL419_000640) letA 33002..33592 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  NL419_RS00645 (NL419_000645) uhpB 33592..35094 (+) 1503 WP_072667477.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  NL419_RS00650 (NL419_000650) uhpC 35104..36423 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  NL419_RS00655 (NL419_000655) uhpT 36561..37952 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=714263 NL419_RS00640 WP_000633668.1 33002..33592(+) (letA) [Escherichia coli strain MLI104K1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=714263 NL419_RS00640 WP_000633668.1 33002..33592(+) (letA) [Escherichia coli strain MLI104K1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378