Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   NPS18_RS05360 Genome accession   NZ_CP101984
Coordinates   1085965..1086654 (-) Length   229 a.a.
NCBI ID   WP_002262198.1    Uniprot ID   Q8DU13
Organism   Streptococcus mutans strain UA-159     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1080965..1091654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS18_RS05330 (NPS18_05330) - 1081216..1081974 (-) 759 WP_002262204.1 inositol monophosphatase family protein -
  NPS18_RS05335 (NPS18_05335) - 1081964..1082242 (-) 279 WP_002279684.1 UPF0223 family protein -
  NPS18_RS05340 (NPS18_05340) spx 1082235..1082648 (-) 414 WP_002263835.1 transcriptional regulator Spx -
  NPS18_RS05345 (NPS18_05345) - 1082709..1083629 (-) 921 WP_002262201.1 bifunctional riboflavin kinase/FAD synthetase -
  NPS18_RS05350 (NPS18_05350) truB 1083660..1084541 (-) 882 WP_002262200.1 tRNA pseudouridine(55) synthase TruB -
  NPS18_RS05355 (NPS18_05355) scnK 1084651..1085964 (-) 1314 WP_002262199.1 sensor histidine kinase KdpD Regulator
  NPS18_RS05360 (NPS18_05360) scnR 1085965..1086654 (-) 690 WP_002262198.1 response regulator transcription factor Regulator
  NPS18_RS05365 (NPS18_05365) - 1086829..1087737 (+) 909 WP_002262197.1 ABC transporter ATP-binding protein -
  NPS18_RS05370 (NPS18_05370) - 1087737..1088477 (+) 741 WP_002262196.1 ABC transporter permease -
  NPS18_RS05375 (NPS18_05375) - 1088474..1089202 (+) 729 WP_002262195.1 ABC transporter permease -
  NPS18_RS05380 (NPS18_05380) - 1089321..1090685 (-) 1365 WP_002262194.1 DUF438 domain-containing protein -
  NPS18_RS05385 (NPS18_05385) - 1090685..1090918 (-) 234 WP_002262193.1 DUF1858 domain-containing protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26243.58 Da        Isoelectric Point: 6.9650

>NTDB_id=713504 NPS18_RS05360 WP_002262198.1 1085965..1086654(-) (scnR) [Streptococcus mutans strain UA-159]
MNYKEKKILILDDNPEILEMVQESLNIAGFNNLTGVQSKKEALEQLGKRSFDLAILDIMLPDGSGFEVLREIRKTSTIPV
LFLSAVSDIEKQYQGFELGADDYIVKPFRPKELELRILSILKRAYPEKDDTLILPTCQVNFSQALITKGELEIQLTAKEY
SILKVLYNNQNRIVTFDQLLEKVWGLQYQGYENTMMAHIRKIRQKIEANPSKPECLLTVKGLGYKLKVS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=713504 NPS18_RS05360 WP_002262198.1 1085965..1086654(-) (scnR) [Streptococcus mutans strain UA-159]
ATGAATTATAAAGAGAAAAAAATCTTAATTTTAGATGACAATCCAGAAATTTTAGAAATGGTGCAAGAGTCTTTAAACAT
TGCTGGTTTTAACAACCTAACAGGCGTGCAATCAAAAAAAGAGGCCTTGGAGCAACTTGGCAAAAGATCCTTTGATTTGG
CCATTTTAGACATTATGCTGCCTGATGGTTCGGGTTTTGAGGTACTAAGAGAAATTCGGAAAACTTCTACTATACCAGTA
CTCTTTTTGTCTGCGGTATCCGACATTGAAAAGCAATACCAAGGTTTTGAGTTGGGAGCGGACGACTACATCGTCAAACC
TTTTCGTCCTAAGGAATTGGAGTTGCGAATCCTTTCTATTTTAAAAAGAGCCTATCCTGAAAAGGACGATACCCTTATTT
TACCTACTTGTCAGGTCAACTTTAGTCAAGCTTTGATTACCAAAGGAGAATTGGAAATTCAGCTGACAGCTAAGGAATAC
AGTATTCTTAAAGTTTTATATAACAATCAAAATCGCATTGTTACCTTTGATCAACTCTTAGAAAAAGTTTGGGGTCTGCA
ATATCAAGGCTATGAAAATACTATGATGGCGCATATTCGCAAGATCAGGCAAAAGATTGAAGCCAATCCTTCTAAGCCAG
AATGTTTACTGACAGTTAAGGGCTTGGGTTACAAACTAAAGGTGAGTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(8-117)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DU13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

100

100

1
  micA Streptococcus pneumoniae Cp1015

38.197

100

0.389
  vicR Streptococcus mutans UA159

36.207

100

0.367