Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   NP431_RS13520 Genome accession   NZ_CP101905
Coordinates   2941818..2942450 (+) Length   210 a.a.
NCBI ID   WP_005381432.1    Uniprot ID   U2ZZI4
Organism   Vibrio natriegens strain 14048     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2936818..2947450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NP431_RS13500 (NP431_13500) - 2938606..2939094 (+) 489 WP_014233185.1 TIGR02444 family protein -
  NP431_RS13505 (NP431_13505) - 2939263..2940270 (+) 1008 WP_020336174.1 hydrolase -
  NP431_RS13510 (NP431_13510) - 2940358..2940570 (+) 213 WP_014233187.1 YheU family protein -
  NP431_RS13515 (NP431_13515) - 2940708..2941577 (+) 870 WP_014233188.1 phosphoribulokinase -
  NP431_RS13520 (NP431_13520) crp 2941818..2942450 (+) 633 WP_005381432.1 cAMP-activated global transcriptional regulator CRP Regulator
  NP431_RS13525 (NP431_13525) - 2942551..2943342 (-) 792 WP_020336177.1 DUF1338 domain-containing protein -
  NP431_RS13530 (NP431_13530) astD 2943728..2945185 (-) 1458 WP_020336178.1 succinylglutamate-semialdehyde dehydrogenase -
  NP431_RS13535 (NP431_13535) astA 2945214..2946233 (-) 1020 WP_014233191.1 arginine N-succinyltransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23665.48 Da        Isoelectric Point: 7.8388

>NTDB_id=712655 NP431_RS13520 WP_005381432.1 2941818..2942450(+) (crp) [Vibrio natriegens strain 14048]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEED
QERTAWVRAKSPCEVAEISFKKFRQLIQVNPDILMRLSAQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=712655 NP431_RS13520 WP_005381432.1 2941818..2942450(+) (crp) [Vibrio natriegens strain 14048]
ATGGTTCTAGGTAAACCTCAAACCGACCCGACATTAGAGTGGTTTCTTTCACACTGTCACATTCATAAGTACCCTTCAAA
GAGCACGCTGATTCACGCAGGTGAAAAAGCTGAAACCTTGTACTACATCGTTAAAGGTTCTGTTGCGGTTCTTATCAAAG
ACGAAGAAGGTAAGGAAATGATCCTTTCTTACCTAAACCAAGGAGACTTTATTGGTGAACTTGGTCTATTCGAGGAAGAC
CAAGAGCGCACAGCTTGGGTTCGAGCTAAATCTCCTTGCGAAGTTGCTGAGATTTCTTTCAAGAAATTCCGTCAGCTTAT
CCAAGTAAACCCAGACATCCTAATGCGTCTTTCTGCGCAGATGGCTCGTCGCCTTCAAGTAACCAGCCAAAAAGTGGGTG
ACCTAGCGTTCCTAGACGTAACTGGTCGTATCGCTCAGACGCTTCTGAACCTTGCAAAACAACCAGACGCGATGACTCAC
CCAGATGGCATGCAAATCAAGATCACTCGTCAAGAAATCGGTCAAATCGTTGGCTGTTCTCGTGAGACAGTTGGTCGTAT
CTTGAAGATGCTAGAAGAGCAGAATCTAATCTCTGCGCACGGTAAAACTATCGTAGTTTACGGTACTCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2ZZI4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

98.095

100

0.981
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.826

98.571

0.471