Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NOV99_RS00360 Genome accession   NZ_CP101844
Coordinates   59567..60484 (+) Length   305 a.a.
NCBI ID   WP_002935296.1    Uniprot ID   -
Organism   Streptococcus suis strain 2018WUSS151     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 60893..66735 59567..60484 flank 409


Gene organization within MGE regions


Location: 59567..66735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NOV99_RS00360 (NOV99_00360) comR 59567..60484 (+) 918 WP_002935296.1 helix-turn-helix domain-containing protein Regulator
  NOV99_RS00365 (NOV99_00365) - 60893..62095 (-) 1203 WP_305880396.1 IS110 family transposase -
  NOV99_RS00370 (NOV99_00370) - 62372..63613 (+) 1242 WP_240020802.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  NOV99_RS00375 (NOV99_00375) - 63782..65305 (+) 1524 WP_240016665.1 quinol oxidase -
  NOV99_RS00380 (NOV99_00380) - 65446..66735 (-) 1290 WP_002935134.1 IS4-like element ISSsu2 family transposase -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 36252.32 Da        Isoelectric Point: 4.6744

>NTDB_id=712295 NOV99_RS00360 WP_002935296.1 59567..60484(+) (comR) [Streptococcus suis strain 2018WUSS151]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIVVDTLCSLFDVLDTDSQEYGKEILDDYLHQSYHRSKLSIND
LMILRLFIEHCQLEDLSVGTSNYALFTDLIEKLPQSIYDVHSESLFIVRDLFLAIVRILFSKELYNHIPVYIEKIENIME
LSQDFQKKPILNLVKWKYELKVQHNHEIAERYYNEAITFASLLNQFHLKEKLQMEWEKDTQSLKR

Nucleotide


Download         Length: 918 bp        

>NTDB_id=712295 NOV99_RS00360 WP_002935296.1 59567..60484(+) (comR) [Streptococcus suis strain 2018WUSS151]
ATGAACGATAAGGAGTTTGGACAGCGTGTGCGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAAATAGTTGTAGACACCCTATGTTCCCTATTTGATGTATTGGATACAG
ATAGCCAGGAATACGGTAAAGAAATTCTTGATGATTATTTACATCAAAGCTATCACCGTTCCAAACTATCTATAAACGAT
TTAATGATTTTGCGATTATTTATTGAACATTGTCAGTTGGAGGATTTATCTGTTGGAACTTCCAATTATGCTTTATTTAC
AGATTTGATAGAGAAATTGCCTCAATCAATCTATGATGTACATTCGGAATCCTTATTCATTGTCCGCGATTTATTTCTAG
CTATTGTTCGTATTTTATTTTCGAAGGAGTTGTATAATCATATTCCAGTCTATATAGAAAAAATAGAAAACATCATGGAA
TTATCACAAGATTTTCAGAAGAAGCCAATTCTAAATCTTGTGAAATGGAAATATGAATTAAAGGTACAACATAATCATGA
AATTGCTGAGAGGTACTATAATGAAGCGATTACATTTGCCAGCCTACTAAATCAATTTCACTTGAAAGAAAAACTGCAAA
TGGAATGGGAAAAAGATACGCAGAGTCTAAAAAGATGA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis D9

100

100

1
  comR Streptococcus suis P1/7

62.126

98.689

0.613
  comR Streptococcus suis 05ZYH33

62.126

98.689

0.613
  comR Streptococcus mutans UA159

37

98.361

0.364