Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   K6J62_RS00175 Genome accession   NZ_AP018779
Coordinates   39760..40434 (-) Length   224 a.a.
NCBI ID   WP_110431775.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-8 isolate 10H15     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34760..45434
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J62_RS00155 (CHBNIII8_00310) hinT 36465..36815 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  K6J62_RS00160 (CHBNIII8_00320) - 36815..37165 (+) 351 WP_005647993.1 DUF1425 domain-containing protein -
  K6J62_RS00165 (CHBNIII8_00330) nagZ 37169..38224 (+) 1056 WP_110426325.1 beta-N-acetylhexosaminidase -
  K6J62_RS00170 (CHBNIII8_00340) rlmC 38217..39395 (+) 1179 WP_110426324.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  K6J62_RS00175 (CHBNIII8_00350) crp 39760..40434 (-) 675 WP_110431775.1 cAMP-activated global transcriptional regulator CRP Regulator
  K6J62_RS00180 (CHBNIII8_00360) - 40419..40670 (-) 252 WP_005647999.1 YheU family protein -
  K6J62_RS00185 (CHBNIII8_00370) slmA 40692..41348 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  K6J62_RS00190 (CHBNIII8_00380) dut 41352..41807 (-) 456 WP_005631431.1 dUTP diphosphatase -
  K6J62_RS00195 (CHBNIII8_00390) coaBC 41855..43057 (-) 1203 WP_110431774.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  K6J62_RS00200 (CHBNIII8_00400) radC 43221..43886 (+) 666 WP_032821549.1 DNA repair protein RadC -
  K6J62_RS00205 (CHBNIII8_00410) rpmB 44100..44336 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  K6J62_RS00210 (CHBNIII8_00420) rpmG 44348..44518 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25207.91 Da        Isoelectric Point: 6.7511

>NTDB_id=71229 K6J62_RS00175 WP_110431775.1 39760..40434(-) (crp) [Haemophilus influenzae strain CHBN-III-8 isolate 10H15]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIYAHGKTIVVYGTR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=71229 K6J62_RS00175 WP_110431775.1 39760..40434(-) (crp) [Haemophilus influenzae strain CHBN-III-8 isolate 10H15]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCTACGCTC
ATGGAAAAACAATCGTTGTATATGGCACAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

99.107

100

0.991
  crp Vibrio cholerae strain A1552

75.98

91.071

0.692
  crp Acinetobacter baumannii D1279779

48.718

87.054

0.424

Multiple sequence alignment