Detailed information NTG0711643

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: POF59_RS01150
• Genome accession: NZ_CP116712
• Coordinates: 192145..192606 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKO
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 187145..197606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
POF59_RS01120 (POF59_01120)	-	188761..189126 (+)	366	WP_000285373.1	DUF1033 family protein	-
POF59_RS01125 (POF59_01125)	comGA	189298..190269 (+)	972	WP_000250801.1	competence type IV pilus ATPase ComGA	Machinery gene
POF59_RS01130 (POF59_01130)	comGB	190163..191206 (+)	1044	WP_228313184.1	competence type IV pilus assembly protein ComGB	Machinery gene
POF59_RS01135 (POF59_01135)	comGC/cglC	191203..191532 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
POF59_RS01140 (POF59_01140)	comGD	191507..191920 (+)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
POF59_RS01145 (POF59_01145)	comGE	191892..192191 (+)	300	WP_038406052.1	competence type IV pilus minor pilin ComGE	Machinery gene
POF59_RS01150 (POF59_01150)	comGF	192145..192606 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
POF59_RS01155 (POF59_01155)	comGG	192584..192955 (+)	372	WP_000601105.1	competence type IV pilus minor pilin ComGG	Machinery gene
POF59_RS01160 (POF59_01160)	comGH	193070..194044 (+)	975	WP_001008567.1	class I SAM-dependent methyltransferase	Machinery gene
POF59_RS01165 (POF59_01165)	-	194076..195269 (+)	1194	WP_000047534.1	acetate kinase	-
POF59_RS01170 (POF59_01170)	-	195397..195589 (+)	193	Protein_174	helix-turn-helix transcriptional regulator	-
POF59_RS01175 (POF59_01175)	-	195568..195834 (+)	267	Protein_175	hypothetical protein	-
POF59_RS01180 (POF59_01180)	-	195903..196568 (+)	666	WP_000008107.1	type II CAAX endopeptidase family protein	-
POF59_RS01185 (POF59_01185)	proC	196589..197359 (-)	771	WP_001876660.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=711643 POF59_RS01150 WP_001874060.1 192145..192606(+) (comGF) [Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKO]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=711643 POF59_RS01150 WP_001874060.1 192145..192606(+) (comGF) [Streptococcus agalactiae strain CNCTC 10/84 Cas9 AEKO]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTGCTAGTTTATCAAGGACTAACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTCGAAGGCGCTCACTTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTTCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373