Detailed information NTG0071159

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: K6J69_RS00180
• Genome accession: NZ_AP018777
• Coordinates: 40619..41293 (-)
• Length: 224 a.a.
• NCBI ID: WP_105896651.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain CHBN-III-6 isolate 13H31
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 35619..46293

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J69_RS00155 (CHBNIII6_00310)	-	36930..37280 (+)	351	WP_050846704.1	HIT domain-containing protein	-
K6J69_RS00160 (CHBNIII6_00320)	-	37280..37630 (+)	351	WP_110431320.1	YcfL family protein	-
K6J69_RS00165 (CHBNIII6_00330)	nagZ	37634..38686 (+)	1053	WP_110431321.1	beta-N-acetylhexosaminidase	-
K6J69_RS00170 (CHBNIII6_00340)	rlmC	38683..39870 (+)	1188	WP_110431322.1	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	-
K6J69_RS00175 (CHBNIII6_00350)	-	39904..40227 (+)	324	WP_050848408.1	cupin domain-containing protein	-
K6J69_RS00180 (CHBNIII6_00360)	crp	40619..41293 (-)	675	WP_105896651.1	cAMP-activated global transcriptional regulator CRP	Regulator
K6J69_RS00185 (CHBNIII6_00370)	-	41278..41529 (-)	252	WP_110431323.1	YheU family protein	-
K6J69_RS00190 (CHBNIII6_00380)	slmA	41551..42207 (-)	657	WP_110431324.1	nucleoid occlusion factor SlmA	-
K6J69_RS00195 (CHBNIII6_00390)	dut	42211..42666 (-)	456	WP_044330861.1	dUTP diphosphatase	-
K6J69_RS00200 (CHBNIII6_00400)	coaBC	42838..44052 (-)	1215	WP_110431325.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
K6J69_RS00205 (CHBNIII6_00410)	radC	44215..44880 (+)	666	WP_110431326.1	RadC family protein	-
K6J69_RS00210 (CHBNIII6_00420)	rpmB	45093..45329 (+)	237	WP_005542826.1	50S ribosomal protein L28	-
K6J69_RS00215 (CHBNIII6_00430)	rpmG	45341..45511 (+)	171	WP_005613503.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25123.80 Da
• Isoelectric Point: 6.8373

>NTDB_id=71159 K6J69_RS00180 WP_105896651.1 40619..41293(-) (crp) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 675 bp

>NTDB_id=71159 K6J69_RS00180 WP_105896651.1 40619..41293(-) (crp) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAGGCAACTCAACGGGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGTCAAGAAAT
AGGGCAAATGGTGGGGTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	99.107	100	0.991
crp	Vibrio cholerae strain A1552	75.98	91.071	0.692
crp	Acinetobacter baumannii D1279779	47.668	86.161	0.411