Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   K6J70_RS00175 Genome accession   NZ_AP018774
Coordinates   39712..40386 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain CHBN-III-3 isolate 13H42     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34712..45386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J70_RS00155 (CHBNIII3_00310) - 36416..36766 (+) 351 WP_005686227.1 HIT domain-containing protein -
  K6J70_RS00160 (CHBNIII3_00320) - 36766..37116 (+) 351 WP_005686225.1 DUF1425 domain-containing protein -
  K6J70_RS00165 (CHBNIII3_00330) nagZ 37120..38172 (+) 1053 WP_005686223.1 beta-N-acetylhexosaminidase -
  K6J70_RS00170 (CHBNIII3_00340) rlmC 38169..39347 (+) 1179 WP_005686221.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  K6J70_RS00175 (CHBNIII3_00350) crp 39712..40386 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  K6J70_RS00180 (CHBNIII3_00360) - 40371..40622 (-) 252 WP_005647999.1 YheU family protein -
  K6J70_RS00185 (CHBNIII3_00370) slmA 40644..41300 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  K6J70_RS00190 (CHBNIII3_00380) dut 41304..41759 (-) 456 WP_005631431.1 dUTP diphosphatase -
  K6J70_RS00195 (CHBNIII3_00390) coaBC 41807..43009 (-) 1203 WP_012054541.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  K6J70_RS00200 (CHBNIII3_00400) radC 43173..43838 (+) 666 WP_110439955.1 DNA repair protein RadC -
  K6J70_RS00205 (CHBNIII3_00410) rpmB 44051..44287 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  K6J70_RS00210 (CHBNIII3_00420) rpmG 44299..44469 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=71053 K6J70_RS00175 WP_005647998.1 39712..40386(-) (crp) [Haemophilus influenzae strain CHBN-III-3 isolate 13H42]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=71053 K6J70_RS00175 WP_005647998.1 39712..40386(-) (crp) [Haemophilus influenzae strain CHBN-III-3 isolate 13H42]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTACGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment