Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E5Q65_RS14635 Genome accession   NZ_CP116480
Coordinates   3024221..3024811 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain GTEN_24     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3019221..3029811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5Q65_RS14620 uhpT 3019743..3021134 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  E5Q65_RS14625 uhpC 3021390..3022709 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  E5Q65_RS14630 uhpB 3022719..3024221 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  E5Q65_RS14635 letA 3024221..3024811 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  E5Q65_RS14640 ilvN 3024886..3025176 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  E5Q65_RS14645 ilvB 3025180..3026868 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  E5Q65_RS14650 ivbL 3026974..3027072 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  E5Q65_RS14655 tisB 3027636..3027725 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  E5Q65_RS14660 ysdE 3027988..3028062 (-) 75 WP_211180519.1 protein YsdE -
  E5Q65_RS14665 emrD 3028144..3029328 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=710295 E5Q65_RS14635 WP_000633668.1 3024221..3024811(-) (letA) [Escherichia coli strain GTEN_24]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=710295 E5Q65_RS14635 WP_000633668.1 3024221..3024811(-) (letA) [Escherichia coli strain GTEN_24]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378