Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PL330_RS00155 Genome accession   NZ_CP116411
Coordinates   29505..30095 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain HH45     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 24505..35095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PL330_RS00120 (PL330_00120) yidG 24681..25043 (+) 363 WP_001113432.1 DUF202 domain-containing protein -
  PL330_RS00125 (PL330_00125) yidF 25040..25537 (+) 498 WP_000148063.1 radical SAM protein -
  PL330_RS00130 (PL330_00130) emrD 25545..26729 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PL330_RS00135 (PL330_00135) ysdE 26811..26885 (+) 75 WP_211180519.1 protein YsdE -
  PL330_RS00140 (PL330_00140) ivbL 27244..27342 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  PL330_RS00145 (PL330_00145) ilvB 27448..29136 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  PL330_RS00150 (PL330_00150) ilvN 29140..29430 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PL330_RS00155 (PL330_00155) letA 29505..30095 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PL330_RS00160 (PL330_00160) uhpB 30095..31597 (+) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PL330_RS00165 (PL330_00165) uhpC 31607..32926 (+) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PL330_RS00170 (PL330_00170) uhpT 33064..34454 (+) 1391 Protein_33 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=710070 PL330_RS00155 WP_000633668.1 29505..30095(+) (letA) [Escherichia coli strain HH45]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=710070 PL330_RS00155 WP_000633668.1 29505..30095(+) (letA) [Escherichia coli strain HH45]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378