Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PL329_RS01520 Genome accession   NZ_CP116409
Coordinates   322947..323537 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain HH97     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 317947..328537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PL329_RS01485 (PL329_01485) yidG 318147..318509 (+) 363 WP_001113432.1 DUF202 domain-containing protein -
  PL329_RS01490 (PL329_01490) yidF 318506..319003 (+) 498 WP_000148063.1 radical SAM protein -
  PL329_RS01495 (PL329_01495) emrD 319011..320195 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PL329_RS01500 (PL329_01500) ysdE 320277..320351 (+) 75 WP_211180519.1 protein YsdE -
  PL329_RS01505 (PL329_01505) ivbL 320685..320783 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PL329_RS01510 (PL329_01510) ilvB 320889..322577 (+) 1689 WP_000168474.1 acetolactate synthase large subunit -
  PL329_RS01515 (PL329_01515) ilvN 322581..322871 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PL329_RS01520 (PL329_01520) letA 322947..323537 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PL329_RS01525 (PL329_01525) uhpB 323537..325039 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PL329_RS01530 (PL329_01530) uhpC 325049..326368 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PL329_RS01535 (PL329_01535) uhpT 326506..327897 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=710001 PL329_RS01520 WP_000633668.1 322947..323537(+) (letA) [Escherichia coli strain HH97]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=710001 PL329_RS01520 WP_000633668.1 322947..323537(+) (letA) [Escherichia coli strain HH97]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378