Detailed information NTG0709506

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NMT99_RS18235
• Genome accession: NZ_CP101290
• Coordinates: 3516768..3517925 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain LjM2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3511768..3522925

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMT99_RS18205	yvyF	3512024..3512440 (-)	417	WP_259597028.1	TIGR03826 family flagellar region protein	-
NMT99_RS18210	comFC	3512514..3513236 (-)	723	WP_029725992.1	comF operon protein ComFC	Machinery gene
NMT99_RS18215	comFB	3513200..3513496 (-)	297	WP_015483764.1	late competence protein ComFB	-
NMT99_RS18220	comFA	3513556..3514947 (-)	1392	WP_029725993.1	ATP-dependent helicase ComFA	Machinery gene
NMT99_RS18225	fakBA	3515053..3515898 (-)	846	WP_003227986.1	DegV family protein	-
NMT99_RS18230	degU	3515996..3516685 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NMT99_RS18235	degS	3516768..3517925 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
NMT99_RS18240	yvyE	3518142..3518795 (+)	654	WP_003227979.1	YigZ family protein	-
NMT99_RS18245	tagV	3518795..3519970 (+)	1176	WP_003227977.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
NMT99_RS18250	tagO	3520043..3521119 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
NMT99_RS18255	tuaH	3521264..3522457 (-)	1194	WP_072692828.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=709506 NMT99_RS18235 WP_003227983.1 3516768..3517925(-) (degS) [Bacillus subtilis strain LjM2]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=709506 NMT99_RS18235 WP_003227983.1 3516768..3517925(-) (degS) [Bacillus subtilis strain LjM2]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATCGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1