Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PH192_RS15555 Genome accession   NZ_CP116241
Coordinates   3209966..3210556 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain 7.1994/NIST0056     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3204966..3215556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PH192_RS15525 (PH192_15520) emrD 3205448..3206632 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  PH192_RS15530 (PH192_15525) ysdE 3206714..3206788 (+) 75 WP_211180519.1 protein YsdE -
  PH192_RS15535 (PH192_15530) tisB 3207051..3207140 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PH192_RS15540 (PH192_15535) ivbL 3207705..3207803 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  PH192_RS15545 (PH192_15540) ilvB 3207909..3209597 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  PH192_RS15550 (PH192_15545) ilvN 3209601..3209891 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PH192_RS15555 (PH192_15550) letA 3209966..3210556 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PH192_RS15560 (PH192_15555) uhpB 3210556..3212058 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PH192_RS15565 (PH192_15560) uhpC 3212068..3213387 (+) 1320 WP_001296914.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PH192_RS15570 (PH192_15565) uhpT 3213525..3214916 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=709391 PH192_RS15555 WP_000633668.1 3209966..3210556(+) (letA) [Escherichia coli strain 7.1994/NIST0056]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=709391 PH192_RS15555 WP_000633668.1 3209966..3210556(+) (letA) [Escherichia coli strain 7.1994/NIST0056]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378