Detailed information NTG0070927

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: H7680_RS02855
• Genome accession: NZ_AP023394
• Coordinates: 541442..542794 (+)
• Length: 450 a.a.
• NCBI ID: WP_014612101.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 159
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 536442..547794

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7680_RS02830 (SDSE159_05150)	-	537509..538156 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
H7680_RS02835 (SDSE159_05160)	-	538171..538872 (-)	702	WP_003057191.1	amino acid ABC transporter permease	-
H7680_RS02840 (SDSE159_05170)	-	538886..539686 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
H7680_RS02845 (SDSE159_05180)	-	539686..540480 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
H7680_RS02850 (SDSE159_05190)	yycF	540739..541449 (+)	711	WP_150336165.1	response regulator YycF	-
H7680_RS02855 (SDSE159_05200)	vicK	541442..542794 (+)	1353	WP_014612101.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H7680_RS02860 (SDSE159_05210)	vicX	542798..543607 (+)	810	WP_003057211.1	MBL fold metallo-hydrolase	Regulator
H7680_RS02865 (SDSE159_05220)	rnc	544365..545057 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.06 Da
• Isoelectric Point: 5.7411

>NTDB_id=70927 H7680_RS02855 WP_014612101.1 541442..542794(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=70927 H7680_RS02855 WP_014612101.1 541442..542794(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterProScan.

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.188	92	0.673
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629