Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC02_RS22410 Genome accession   NZ_CP116176
Coordinates   4627835..4628425 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DETEC-E601     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4622835..4633425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC02_RS22395 (PIC02_22390) uhpT 4623475..4624866 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PIC02_RS22400 (PIC02_22395) uhpC 4625004..4626323 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC02_RS22405 (PIC02_22400) uhpB 4626333..4627835 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC02_RS22410 (PIC02_22405) letA 4627835..4628425 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIC02_RS22415 (PIC02_22410) ilvN 4628500..4628790 (-) 291 WP_001181713.1 acetolactate synthase small subunit -
  PIC02_RS22420 (PIC02_22415) ilvB 4628794..4630482 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  PIC02_RS22425 (PIC02_22420) ivbL 4630588..4630686 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  PIC02_RS22430 (PIC02_22425) tisB 4631251..4631340 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PIC02_RS22435 (PIC02_22430) ysdE 4631603..4631677 (-) 75 WP_211180519.1 protein YsdE -
  PIC02_RS22440 (PIC02_22435) emrD 4631759..4632943 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=708774 PIC02_RS22410 WP_000633668.1 4627835..4628425(-) (letA) [Escherichia coli strain DETEC-E601]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=708774 PIC02_RS22410 WP_000633668.1 4627835..4628425(-) (letA) [Escherichia coli strain DETEC-E601]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378