Detailed information NTG0070825

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: H7678_RS02915
• Genome accession: NZ_AP023393
• Coordinates: 551038..552390 (+)
• Length: 450 a.a.
• NCBI ID: WP_003060939.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 89
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 546038..557390

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7678_RS02890 (SDSE89_05260)	-	547105..547752 (-)	648	WP_046177436.1	amino acid ABC transporter permease	-
H7678_RS02895 (SDSE89_05270)	-	547767..548468 (-)	702	WP_003057191.1	amino acid ABC transporter permease	-
H7678_RS02900 (SDSE89_05280)	-	548482..549282 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
H7678_RS02905 (SDSE89_05290)	-	549282..550076 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
H7678_RS02910 (SDSE89_05300)	yycF	550335..551045 (+)	711	WP_003049952.1	response regulator YycF	-
H7678_RS02915 (SDSE89_05310)	vicK	551038..552390 (+)	1353	WP_003060939.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H7678_RS02920 (SDSE89_05320)	vicX	552394..553203 (+)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
H7678_RS02925 (SDSE89_05330)	rnc	553961..554653 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.02 Da
• Isoelectric Point: 5.5557

>NTDB_id=70825 H7678_RS02915 WP_003060939.1 551038..552390(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=70825 H7678_RS02915 WP_003060939.1 551038..552390(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATTTGACCAAGGAGCAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCCCCAAGTTTTATCAAGGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-165)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.43	92	0.676
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629