Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC52_RS14740 Genome accession   NZ_CP116100
Coordinates   3049077..3049667 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DETEC-P881     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3044077..3054667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC52_RS14715 (PIC52_14715) ysdE 3045162..3045236 (+) 75 WP_211180519.1 protein YsdE -
  PIC52_RS14720 (PIC52_14720) ivbL 3045481..3045579 (+) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PIC52_RS14725 (PIC52_14725) ilvB 3045685..3047373 (+) 1689 WP_000168473.1 acetolactate synthase large subunit -
  PIC52_RS14730 (PIC52_14730) ilvN 3047377..3047667 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIC52_RS14735 (PIC52_14735) - 3047733..3048593 (-) 861 WP_001525915.1 DUF6708 domain-containing protein -
  PIC52_RS14740 (PIC52_14740) letA 3049077..3049667 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIC52_RS14745 (PIC52_14745) uhpB 3049667..3051169 (+) 1503 WP_271287338.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC52_RS14750 (PIC52_14750) uhpC 3051179..3052498 (+) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC52_RS14755 (PIC52_14755) uhpT 3052636..3054027 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=707771 PIC52_RS14740 WP_000633668.1 3049077..3049667(+) (letA) [Escherichia coli strain DETEC-P881]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=707771 PIC52_RS14740 WP_000633668.1 3049077..3049667(+) (letA) [Escherichia coli strain DETEC-P881]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCTGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACAGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378