Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC78_RS22630 Genome accession   NZ_CP116094
Coordinates   4677599..4678189 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DETEC-S560     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4672599..4683189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC78_RS22615 (PIC78_22610) uhpT 4673239..4674630 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PIC78_RS22620 (PIC78_22615) uhpC 4674768..4676087 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC78_RS22625 (PIC78_22620) uhpB 4676097..4677599 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC78_RS22630 (PIC78_22625) letA 4677599..4678189 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIC78_RS22635 (PIC78_22630) ilvN 4678264..4678554 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIC78_RS22640 (PIC78_22635) ilvB 4678558..4680246 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  PIC78_RS22645 (PIC78_22640) ivbL 4680352..4680450 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  PIC78_RS22650 (PIC78_22645) - 4680842..4682062 (+) 1221 WP_000343760.1 ISL3-like element ISKox3 family transposase -
  PIC78_RS22655 (PIC78_22650) tisB 4682339..4682428 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  PIC78_RS22660 (PIC78_22655) ysdE 4682552..4682626 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=707712 PIC78_RS22630 WP_000633668.1 4677599..4678189(-) (letA) [Escherichia coli strain DETEC-S560]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=707712 PIC78_RS22630 WP_000633668.1 4677599..4678189(-) (letA) [Escherichia coli strain DETEC-S560]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378