Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   H7679_RS08040 Genome accession   NZ_AP023392
Coordinates   1642226..1642909 (-) Length   227 a.a.
NCBI ID   WP_012027525.1    Uniprot ID   A0A0H3MWH7
Organism   Streptococcus suis strain DAT300     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1637226..1647909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS08015 (DAT300_15500) - 1637714..1638031 (-) 318 WP_024389134.1 PadR family transcriptional regulator -
  H7679_RS08020 (DAT300_15510) - 1638028..1638192 (-) 165 WP_024389133.1 hypothetical protein -
  H7679_RS08025 (DAT300_15520) - 1638382..1640385 (-) 2004 WP_024396160.1 ABC transporter permease -
  H7679_RS08030 (DAT300_15530) - 1640387..1641145 (-) 759 WP_024396159.1 ABC transporter ATP-binding protein -
  H7679_RS08035 (DAT300_15540) - 1641241..1642233 (-) 993 WP_024396158.1 sensor histidine kinase -
  H7679_RS08040 (DAT300_15550) braR 1642226..1642909 (-) 684 WP_012027525.1 response regulator transcription factor Regulator
  H7679_RS08045 (DAT300_15560) - 1643079..1644248 (+) 1170 WP_024396157.1 DUF2974 domain-containing protein -
  H7679_RS08050 (DAT300_15570) - 1644263..1645387 (-) 1125 WP_024396156.1 aminotransferase -
  H7679_RS08055 (DAT300_15580) - 1645535..1646296 (-) 762 WP_024396155.1 nuclear transport factor 2 family protein -
  H7679_RS08060 (DAT300_15590) - 1646306..1647817 (-) 1512 WP_024396154.1 ABC transporter permease/substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26581.80 Da        Isoelectric Point: 4.5525

>NTDB_id=70764 H7679_RS08040 WP_012027525.1 1642226..1642909(-) (braR) [Streptococcus suis strain DAT300]
MQKILLIEDDKTISQLVAKNLINWGYQVQEVKDFQMVLEQMEEFQPHLILLDIGLPFFNGYYWCQEIRKTSRVPIMFLSS
HDQPMDIVMAINMGADDYVTKPFEMTVLLAKIQGLLRRTYDFVGEQSLLWFEEISLDLKTMQVSYGQVVEELTRNEFQIL
RVLFEHGKEVVSREELMRELWNSDIFVDDNTLSVNIARLRKKLAELDLPDVIATKKGVGYGLVWTHE

Nucleotide


Download         Length: 684 bp        

>NTDB_id=70764 H7679_RS08040 WP_012027525.1 1642226..1642909(-) (braR) [Streptococcus suis strain DAT300]
ATGCAGAAAATTCTTCTTATCGAGGATGATAAAACGATTAGCCAACTAGTTGCTAAAAACTTGATAAACTGGGGTTACCA
GGTGCAAGAGGTCAAGGATTTTCAGATGGTTTTGGAACAGATGGAAGAGTTTCAGCCCCATTTGATTTTACTGGATATCG
GCCTGCCTTTTTTCAATGGCTATTACTGGTGTCAGGAAATTCGCAAGACATCCCGTGTGCCCATTATGTTTCTATCTTCC
CATGATCAGCCAATGGATATTGTTATGGCGATCAATATGGGGGCGGATGACTATGTGACCAAGCCCTTTGAAATGACGGT
TCTCCTGGCCAAAATACAGGGGCTTCTCAGAAGAACCTATGACTTTGTCGGAGAACAAAGTTTACTCTGGTTTGAGGAGA
TTTCCCTAGACCTAAAGACCATGCAGGTGTCCTATGGACAGGTTGTGGAAGAGCTGACGCGAAATGAATTTCAGATTTTA
CGGGTGCTTTTTGAACATGGCAAGGAAGTGGTCAGCCGTGAGGAGCTGATGAGAGAACTCTGGAACAGTGATATTTTTGT
GGATGACAATACTTTGTCGGTTAACATCGCTCGCCTGCGTAAGAAATTGGCAGAACTGGATCTGCCAGATGTGATTGCGA
CCAAGAAAGGAGTAGGCTACGGCCTGGTGTGGACACATGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MWH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

47.706

96.035

0.458
  vicR Streptococcus mutans UA159

39.13

100

0.396
  micA Streptococcus pneumoniae Cp1015

37.991

100

0.383

Multiple sequence alignment