Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC22_RS15365 Genome accession   NZ_CP116088
Coordinates   3113227..3113817 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DETEC-S565     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3108227..3118817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC22_RS15350 (PIC22_15345) uhpT 3108867..3110258 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  PIC22_RS15355 (PIC22_15350) uhpC 3110396..3111715 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC22_RS15360 (PIC22_15355) uhpB 3111725..3113227 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC22_RS15365 (PIC22_15360) letA 3113227..3113817 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIC22_RS15370 (PIC22_15365) ilvN 3113892..3114182 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIC22_RS15375 (PIC22_15370) ilvB 3114186..3115874 (-) 1689 WP_000168432.1 acetolactate synthase large subunit -
  PIC22_RS15380 (PIC22_15375) ivbL 3115980..3116078 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  PIC22_RS15385 (PIC22_15380) tisB 3116642..3116731 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  PIC22_RS15390 (PIC22_15385) ysdE 3116994..3117068 (-) 75 WP_211180519.1 protein YsdE -
  PIC22_RS15395 (PIC22_15390) emrD 3117150..3118334 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=707613 PIC22_RS15365 WP_000633668.1 3113227..3113817(-) (letA) [Escherichia coli strain DETEC-S565]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=707613 PIC22_RS15365 WP_000633668.1 3113227..3113817(-) (letA) [Escherichia coli strain DETEC-S565]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378