Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC49_RS00185 Genome accession   NZ_CP116074
Coordinates   36900..37490 (+) Length   196 a.a.
NCBI ID   WP_000633675.1    Uniprot ID   -
Organism   Escherichia coli strain DETEC-S586     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 31900..42490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC49_RS00170 (PIC49_00170) ilvN 33143..33433 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIC49_RS00175 (PIC49_00175) - 34511..34993 (+) 483 WP_038428612.1 hypothetical protein -
  PIC49_RS00180 (PIC49_00180) - 35269..36738 (+) 1470 WP_001309856.1 hypothetical protein -
  PIC49_RS00185 (PIC49_00185) letA 36900..37490 (+) 591 WP_000633675.1 transcriptional regulator UhpA Regulator
  PIC49_RS00190 (PIC49_00190) uhpB 37490..38992 (+) 1503 WP_001322651.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIC49_RS00195 (PIC49_00195) uhpC 39002..40321 (+) 1320 WP_001309854.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIC49_RS00200 (PIC49_00200) uhpT 40459..41850 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20905.30 Da        Isoelectric Point: 5.9982

>NTDB_id=707396 PIC49_RS00185 WP_000633675.1 36900..37490(+) (letA) [Escherichia coli strain DETEC-S586]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELISAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=707396 PIC49_RS00185 WP_000633675.1 36900..37490(+) (letA) [Escherichia coli strain DETEC-S586]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGTTGCTGGGGCTGGAACCTGATTT
GCAAGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTGATTTCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTAGGTTTGTCGCCAAAAACTGTGCATGTACATCGTGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38

100

0.388
  letA Legionella pneumophila strain ERS1305867

38

100

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378